N-溴代丁二酰亚胺(NBS) → HCID 68405898，化合物

反应方程式

[CH3:1][C:2]1[NH:6][C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])=[N:4][CH:3]=1.C1C(=O)N([Br:19])C(=O)C1>>[Br:19][C:3]1[N:4]=[C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])[NH:6][C:2]=1[CH3:1]

参与物

反应物 2

HCID 67184N-溴代丁二酰亚胺(NBS)

HCID 249744664-甲基-1H-咪唑-2甲酸乙酯2 次

产物 1

HCID 68405898HCID 68405898，化合物收率 94%

实验过程

The same operation as in Example (1c) was performed using ethyl 5-methyl-1H-imidazole-2-carboxylate obtained by the method described in Example (5a) (0.30 g, 1.95 mmol) and NBS (0.35 g, 1.96 mmol), to obtain 0.43 g of the title compound as a white solid (94%).

后处理

customobtained by the method

来源与证据

ORD记录: ord-5d7a2877e4a8420aae1b3eb03c7104f3
来源数据集: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US08927588B2

反应笔记

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