4-叔丁基苄醇 → HCID 57118008，化合物

HRID 1458194

反应方程式

HRID 1458194 反应方程式
[C:1](Cl)(=[O:5])[C:2]([Cl:4])=[O:3].[C:7]([C:11]1[CH:18]=[CH:17][C:14]([CH2:15][OH:16])=[CH:13][CH:12]=1)([CH3:10])([CH3:9])[CH3:8]>C(OCC)C>[C:7]([C:11]1[CH:12]=[CH:13][C:14]([CH2:15][O:16][C:1](=[O:5])[C:2]([Cl:4])=[O:3])=[CH:17][CH:18]=1)([CH3:10])([CH3:8])[CH3:9]

参与物

4

反应物 2

HCID 134164-叔丁基苄醇HCID 65578草酰氯

产物 1

HCID 57118008HCID 57118008，化合物

试剂、催化剂与溶剂 1

HCID 3283乙醚溶剂2 次

实验过程

To a stirred solution of oxalyl dichloride (100ml) in diethylether (500 ml) at -10° under nitrogen a solution of 4-t-butylbenzyl alcohol (200 ml) in diethylether (100 ml) was added dropwise so as to maintain the temperature between -10° and -5°. The solvent was then evaporated under vacuum to give the title compound (289 g,) as a clear oil (b.p. 120°-122° at 2 mbar).

后处理

  1. temperatureto maintain the temperature between -10° and -5°
  2. customThe solvent was then evaporated under vacuum

来源与证据

ORD记录
ord-552cfa4c7d574c2cae876c5253dbc6fa
来源数据集
uspto-grants-1998_12
专利号
US05849907

关联笔记

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