氢溴酸 → (R)-3-(3,4-Dihydroxyphenyl)-2-propylamine hydrobromide

HRID 1523

反应方程式

HRID 1523 反应方程式
C[O:2][C:3]1[CH:4]=[C:5]([CH2:11][C@H:12]([NH2:14])[CH3:13])[CH:6]=[CH:7][C:8]=1[O:9]C.[BrH:15]>>[BrH:15].[OH:2][C:3]1[CH:4]=[C:5]([CH2:11][C@H:12]([NH2:14])[CH3:13])[CH:6]=[CH:7][C:8]=1[OH:9]

参与物

3

反应物 2

HCID 260氢溴酸HCID 11769408(R)-3,4-二甲氧基安非他命

产物 1

HCID 67643451(R)-3-(3,4-Dihydroxyphenyl)-2-propylamine hydrobromide

实验过程

A solution of (R)-3-(3,4-dimethoxyphenyl)-2-propylamine hydrochloride1 (500 mg, 2.15 mMol) in hydrogen bromide (48%, 5 ml) was stirred at 100° C. under an argon atmosphere for 20 hours. After cooling, the solvent was evaporated and the residue was dried giving the title compound.

后处理

  1. temperatureAfter cooling
  2. customthe solvent was evaporated
  3. customthe residue was dried

来源与证据

ORD记录
ord-a3c93df638364213adea34d2adfb06d5
来源数据集
uspto-grants-1998_03
专利号
US05726165

关联笔记

加载中…