乙二胺 → HCID 13715405，化合物

HRID 1607124笔记

反应方程式

HRID 1607124 反应方程式
[NH2:1][CH2:2][CH2:3][NH2:4].[C:5]1(=[O:10])[O:9][CH:7]([CH3:8])[CH2:6]1>O>[OH:9][CH:7]([CH3:8])[CH2:6][C:5]([NH:1][CH2:2][CH2:3][NH2:4])=[O:10]

参与物

4

反应物 2

HCID 3301乙二胺HCID 18303B-丁内酯

产物 1

HCID 13715405HCID 13715405，化合物

试剂、催化剂与溶剂 1

HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]溶剂

实验过程

192 ml. 1,2-diaminoethane are mixed with 60 ml. water and, with stirring and gentle cooling at 20°-30° C., 74 ml. β-butyrolactone are added dropwise thereto. After 4 days, the reaction mixture is distilled off in a vacuum and the crystal slurry obtained is dried over sulphuric acid in a desiccator. There are obtained 122.4 g. (93% of theory) of the desired base; m.p. 71°-73° C.

后处理

  1. temperaturegentle cooling at 20°-30° C.
  2. distillationthe reaction mixture is distilled off in a vacuum
  3. customthe crystal slurry obtained
  4. dry with materialis dried over sulphuric acid in a desiccator
  5. customThere are obtained 122.4 g

来源与证据

ORD记录
ord-61a5e280000d46e3a80cb0f7f0b61087
来源数据集
uspto-grants-1989_09
专利号
US04863949

反应笔记

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