氯化亚锡二水合物 → (2-Amino-4-cyclopropyl-phenyl)-carbamic acid tert-butyl ester

HRID 1745524笔记

反应方程式

HRID 1745524 反应方程式
[C:1]([O:5][C:6](=[O:20])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:16][CH2:15]2)=[CH:10][C:9]=1[N+:17]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:20])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:16][CH2:15]2)=[CH:10][C:9]=1[NH2:17])([CH3:4])([CH3:2])[CH3:3]

参与物

3

反应物 2

HCID 61436氯化亚锡二水合物HCID 69592793(4-Cyclopropyl-2-nitro-phenyl)-carbamic acid tert.-butyl ester

产物 1

HCID 69592759(2-Amino-4-cyclopropyl-phenyl)-carbamic acid tert-butyl ester

实验过程

Prepared from (4-cyclopropyl-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A3) by reduction with SnCl2.2H2O according to the general procedure G (method b). Obtained as a dark solid (1.96 g).

来源与证据

ORD记录
ord-482a8931b77843dcb776052e4110ebc0
来源数据集
uspto-grants-2006_03
专利号
US07018998B2

反应笔记

加载中…