1-Chloro-2-(diethylamine)ethane hydrochloride → 4-[2-(Diethylamino)ethylthio]-quinazoline

反应方程式

[SH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][N:3]=1.Cl.[CH2:13]([N:15]([CH2:18][CH2:19]Cl)[CH2:16][CH3:17])[CH3:14]>>[CH2:13]([N:15]([CH2:18][CH3:19])[CH2:16][CH2:17][S:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][N:3]=1)[CH3:14]

参与物

反应物 2

HCID 133631-Chloro-2-(diethylamine)ethane hydrochloride

HCID 178527884HCID 178527884，化合物

产物 1

HCID 200436484-[2-(Diethylamino)ethylthio]-quinazoline收率 59.9%

实验过程

The title compound(4.82 g) was prepared from 4-mercaptoquinazoline(5.0 g) and N,N-diethylaminoethylchloride hydrochloride(5.3 g).

来源与证据

ORD记录: ord-3f598ef5caff478f9a7e2dc12b17041f
来源数据集: uspto-grants-1989_05
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US04829069

反应笔记

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