3-甲基吲哚 → 7-chloro-1-methyl-1H-indole

HRID 18278

反应方程式

HRID 18278 反应方程式
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][CH:8]=[CH:7]2.[CH3:11]C1C2C(=CC=CC=2)NC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH3:11])[CH:8]=[CH:7]2

参与物

3

反应物 2

HCID 67363-甲基吲哚HCID 1046447-氯-1H-吲哚

产物 1

HCID 221391057-chloro-1-methyl-1H-indole收率 100%

实验过程

According to the procedure of Preparation 13 (a), except substituting 7-chloroindole for the 3-methylindole, the title compound (2.2 g, 100%) was obtained as a white solid: MS (ES) m/e 166.2 (M+H)+.

来源与证据

ORD记录
ord-e8f8388971ae40ecb68578a66714fe8a
来源数据集
uspto-grants-2010_06
专利号
US07741339B2

关联笔记

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