1,2-二氯乙烷 → N-{3,4-Dioxo-1-phenyl-4-[(2-phenylethyl)amino]butan-2-yl}-2-[3-(4-fluorophenyl)-1H-pyrazol-1-yl]pyridine-3-carboxamide

反应方程式

C(Cl)CCl.ClC(Cl)C(O)=O.[F:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[CH:22]=[CH:21][N:20]([C:23]3[N:52]=[CH:51][CH:50]=[CH:49][C:24]=3[C:25]([NH:27][CH:28]([CH:36]([OH:48])[C:37](=[O:47])[NH:38][CH2:39][CH2:40][C:41]3[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=3)[CH2:29][C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)=[O:26])[N:19]=2)=[CH:14][CH:13]=1.C([O-])(O)=O.[Na+]>CS(C)=O.[Cl-].[Na+].O>[O:48]=[C:36]([C:37](=[O:47])[NH:38][CH2:39][CH2:40][C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1)[CH:28]([NH:27][C:25]([C:24]1[C:23]([N:20]2[CH:21]=[CH:22][C:18]([C:15]3[CH:14]=[CH:13][C:12]([F:11])=[CH:17][CH:16]=3)=[N:19]2)=[N:52][CH:51]=[CH:50][CH:49]=1)=[O:26])[CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1