Hydroxylamine → 1-({3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)azetidin-3-one oxime

反应方程式

[F:1][c:2]1[c:3]([NH:16][c:17]2[c:18]([F:24])[cH:19][c:20]([I:23])[cH:21][cH:22]2)[c:4]([C:9](=[O:10])[N:11]2[CH2:12][C:13](=[O:15])[CH2:14]2)[cH:5][cH:6][c:7]1[F:8].[NH2:25][OH:26].[O:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1>>[F:1][c:2]1[c:3]([NH:16][c:17]2[c:18]([F:24])[cH:19][c:20]([I:23])[cH:21][cH:22]2)[c:4]([C:9](=[O:10])[N:11]2[CH2:12][C:13](=[N:25][OH:26])[CH2:14]2)[cH:5][cH:6][c:7]1[F:8]

参与物

反应物 3

HCID 787Hydroxylamine

HCID 312751,4-二氧六环

HCID 16223411{3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonylazetidin-3-one

产物 1

HCID 162218861-({3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)azetidin-3-one oxime

来源与证据

ORD记录: ord-2950684b7da34404aa1be2d5b1ee2859
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

反应笔记

加载中…