1,3-dipropylxanthine → Diethyl [3-(1,3-dipropylxanthin-7-yl)propyl]phosphonate

HRID 2001笔记

反应方程式

HRID 2001 反应方程式
[CH2:1]([N:4]1[C:13](=[O:14])[C:12]2[NH:11][CH:10]=[N:9][C:8]=2[N:7]([CH2:15][CH2:16][CH3:17])[C:5]1=[O:6])[CH2:2][CH3:3].Br[CH2:19][CH2:20][CH2:21][P:22]([O:27][CH2:28][CH3:29])(=[O:26])[O:23][CH2:24][CH3:25]>>[CH2:1]([N:4]1[C:13](=[O:14])[C:12]2[N:11]([CH2:19][CH2:20][CH2:21][P:22](=[O:26])([O:27][CH2:28][CH3:29])[O:23][CH2:24][CH3:25])[CH:10]=[N:9][C:8]=2[N:7]([CH2:15][CH2:16][CH3:17])[C:5]1=[O:6])[CH2:2][CH3:3]

参与物

3

反应物 2

HCID 1693171,3-dipropylxanthineHCID 283500二乙基(3-溴丙基)膦酸酯

产物 1

HCID 22446304Diethyl [3-(1,3-dipropylxanthin-7-yl)propyl]phosphonate

实验过程

The title substance was prepared from 1,3-dipropylxanthine and diethyl 3-bromopropanephosphonate analogously to Example 1 and chromatographed on silica gel (eluent: ethyl acetate/methanol 20:1).

后处理

  1. customchromatographed on silica gel (eluent: ethyl acetate/methanol 20:1)

来源与证据

ORD记录
ord-37d510efe3de46df8fb8264294561f22
来源数据集
uspto-grants-1998_03
专利号
US05728686

反应笔记

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