三氯甲烷 → Butyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester

HRID 2139151笔记

反应方程式

[CH3:41][CH2:42][CH2:43][CH2:44][N:45]=[C:46]=[O:47].[CH3:48][N:49]([CH3:50])[c:51]1[cH:52][cH:53][n:54][cH:55][cH:56]1.[CH3:61][CH2:62][O:63][C:64](=[O:65])[CH3:66].[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]([S:10](=[O:11])(=[O:12])[NH:13][c:14]2[n:15][c:16](-[c:35]3[cH:36][cH:37][n:38][cH:39][cH:40]3)[n:17][c:18]([O:29][CH2:30][C:31]#[C:32][CH2:33][OH:34])[c:19]2[O:20][c:21]2[c:22]([O:27][CH3:28])[cH:23][cH:24][cH:25][cH:26]2)[n:8][cH:9]1.[CH:57]([Cl:58])([Cl:59])[Cl:60]>>[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]([S:10](=[O:11])(=[O:12])[NH:13][c:14]2[n:15][c:16](-[c:35]3[cH:36][cH:37][n:38][cH:39][cH:40]3)[n:17][c:18]([O:29][CH2:30][C:31]#[C:32][CH2:33][O:34][C:46]([NH:45][CH2:44][CH2:43][CH2:42][CH3:41])=[O:47])[c:19]2[O:20][c:21]2[c:22]([O:27][CH3:28])[cH:23][cH:24][cH:25][cH:26]2)[n:8][cH:9]1