Chloride → Ethyl 2-(1-{[3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazole-4-carboxylate

反应方程式

[CH2:2]([CH3:3])[O:4][C:5](=[O:6])[c:7]1[n:8][c:9]([CH:12]2[CH2:13][CH2:14][NH2+:15][CH2:16][CH2:17]2)[s:10][cH:11]1.[Cl-:1].[F:18][C:19]([c:20]1[n:21][n:22]([CH2:25][C:26](=[O:27])[OH:28])[cH:23][cH:24]1)([F:29])[F:30]>>[CH2:2]([CH3:3])[O:4][C:5](=[O:6])[c:7]1[n:8][c:9]([CH:12]2[CH2:13][CH2:14][N:15]([C:26]([CH2:25][n:22]3[n:21][c:20]([C:19]([F:18])([F:29])[F:30])[cH:24][cH:23]3)=[O:27])[CH2:16][CH2:17]2)[s:10][cH:11]1

参与物

反应物 3

HCID 312Chloride

HCID 2060883[3-(三氟甲基)-1H-吡唑-1-基]乙酸

HCID 178470097HCID 178470097，化合物

产物 1

HCID 58242731Ethyl 2-(1-{[3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazole-4-carboxylate

来源与证据

ORD记录: ord-f8b88c32a7754dcc810d940f23ade897
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

反应笔记

加载中…