乙醇 → [5-(5-Azido-2-fluoro-phenyl)-5-difluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-yl]-carbamic acid tert-butyl ester
反应方程式
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1=[N:13][C:12]([CH:14]([F:15])[F:16])([c:17]2[c:18]([F:24])[cH:19][cH:20][c:21]([Br:23])[cH:22]2)[CH2:11][O:10][CH2:9]1)=[O:25].[C:44]([O:45][CH3:46])([CH3:47])([CH3:48])[CH3:49].[CH3:26][NH:27][CH:28]1[CH2:29][CH2:30][CH2:31][CH2:32][CH:33]1[NH:34][CH3:35].[CH3:40][CH2:41][OH:42].[Cu:50][I:51].[N-:37]=[N+:38]=[N-:39].[Na+:36].[OH2:43]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1=[N:13][C:12]([CH:14]([F:15])[F:16])([c:17]2[c:18]([F:24])[cH:19][cH:20][c:21]([N:37]=[N+:38]=[N-:39])[cH:22]2)[CH2:11][O:10][CH2:9]1)=[O:25]
