溴己烷 → Methyl 5-n-hexyloxy-2-hydroxybenzoate

HRID 264352笔记

反应方程式

HRID 264352 反应方程式
[OH:1][C:2]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].[CH2:13](Br)[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]>>[CH2:13]([O:12][C:9]1[CH:10]=[CH:11][C:2]([OH:1])=[C:3]([CH:8]=1)[C:4]([O:6][CH3:7])=[O:5])[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

参与物

3

反应物 2

HCID 8101溴己烷HCID 750772,5-二羟基苯甲酸甲酯

产物 1

HCID 19036686Methyl 5-n-hexyloxy-2-hydroxybenzoate收率 58%

实验过程

Synthesis was carried out in the same manner as in Example 1, except for replacing methyl 2,4-dihydroxybenzoate with methyl 2,5-dihydroxybenzoate and replacing 2-ethylhexyl bromide with n-hexyl bromide, to obtain methyl 5-n-hexyloxy-2-hydroxybenzoate represented by the following chemical formula (hereinafter referred to as compound 12) as a colorless, clear and oily substance in a yield of 58%. The analytical results are shown below. ##STR33##

后处理

  1. customSynthesis

来源与证据

ORD记录
ord-067a1c54dc8644329a2034184a965103
来源数据集
uspto-grants-1997_07
专利号
US05646184

反应笔记

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