盐酸 → HCID 67703428，化合物
反应方程式
[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:21][CH3:22])=[C:6]2[C:11]=1[O:10][CH2:9][C@H:8]([N:12]([CH:16]([CH2:19][CH3:20])[CH2:17][CH3:18])[CH2:13][CH2:14][CH3:15])[CH2:7]2.[ClH:23]>CCOCC>[ClH:23].[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:21][CH3:22])=[C:6]2[C:11]=1[O:10][CH2:9][C@H:8]([N:12]([CH:16]([CH2:19][CH3:20])[CH2:17][CH3:18])[CH2:13][CH2:14][CH3:15])[CH2:7]2参与物
4
实验过程
(R)-8-Fluoro-5-methoxy-3-(N-3-pentyl-N-n-propylamino)chroman (4.59 g, 14.8 mmol) was dissolved in ether. HCl in ether was added to precipitate the HCl-salt, and gave after drying 4.59 g of (R)-8-fluoro-5-methoxy-3-(N-3-pentyl-N-n-propylamino)chroman hydrochloride as a white powder. Mp. 30°-50° C. (sinters).
后处理
- customto precipitate the HCl-salt
- customgave
- dry with materialafter drying 4.59 g of (R)-8-fluoro-5-methoxy-3-(N-3-pentyl-N-n-propylamino)chroman hydrochloride as a white powder
来源与证据
- ORD记录
- ord-04ebb12081cd4b65ac496c34a918039e
- 来源数据集
- uspto-grants-1997_07
- 专利号
- US05650524
反应笔记
加载中…