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2-氨基 -3-硝基苯甲醚 → 1,2-二氨基-3-甲氧基苯
参与物
| 角色 | 名称 | HCID | 投料 |
|---|---|---|---|
| 反应物 | 2-氨基 -3-硝基苯甲醚 | HCID 85491 | — |
| 催化剂 | 钯 | HCID 23938 | — |
| 溶剂 | 乙酸乙酯 | HCID 8857 | — |
| 产物 | 1,2-二氨基-3-甲氧基苯 | HCID 184268 | 101.9% |
反应步骤
2-Amino-3-nitroanisole (4.3 g) was hydrogenated in ethyl acetate (200 ml) using catalytic 10% palladium on charcoal under an atmosphere of hydrogen at ambient temperature. Once complete the reaction mixture was filtered through Celite and the filtrate evaporated in vacuo to afford the title compound as a brown liquid (3.60 g).
来源与证据
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 专利号 | US06353010B1 |
| 来源数据集 | uspto-grants-2002_03 |
| ORD ID | ord-1931361c855c4e49b5bf142cad92b2bd |
| 来源说明 | uspto-grants-2002_03 |