2-氨基 -3-硝基苯甲醚 → 1,2-二氨基-3-甲氧基苯

HRID 275787

反应方程式

HRID 275787 反应方程式
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][CH:5]=[CH:4][C:3]=1[O:11][CH3:12]>C(OCC)(=O)C.[Pd]>[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][C:3]=1[O:11][CH3:12]

参与物

4

反应物 1

HCID 854912-氨基 -3-硝基苯甲醚

产物 1

HCID 1842681,2-二氨基-3-甲氧基苯收率 101.9%

试剂、催化剂与溶剂 2

HCID 23938钯催化剂HCID 8857乙酸乙酯溶剂

实验过程

2-Amino-3-nitroanisole (4.3 g) was hydrogenated in ethyl acetate (200 ml) using catalytic 10% palladium on charcoal under an atmosphere of hydrogen at ambient temperature. Once complete the reaction mixture was filtered through Celite and the filtrate evaporated in vacuo to afford the title compound as a brown liquid (3.60 g).

后处理

  1. customat ambient temperature
  2. filtrationwas filtered through Celite
  3. customthe filtrate evaporated in vacuo

来源与证据

ORD记录
ord-1931361c855c4e49b5bf142cad92b2bd
来源数据集
uspto-grants-2002_03
专利号
US06353010B1

关联笔记

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