氯化亚砜 → 5-溴呋喃-2-羰酰氯

HRID 34945笔记

反应方程式

HRID 34945 反应方程式
[Br:1][C:2]1[O:6][C:5]([C:7]([OH:9])=O)=[CH:4][CH:3]=1.S(Cl)([Cl:12])=O>C1(C)C=CC=CC=1>[Br:1][C:2]1[O:6][C:5]([C:7]([Cl:12])=[O:9])=[CH:4][CH:3]=1

参与物

4

反应物 2

HCID 24386氯化亚砜HCID 685115-溴-2-糠酸

产物 1

HCID 27570115-溴呋喃-2-羰酰氯

试剂、催化剂与溶剂 1

HCID 1140甲苯溶剂

实验过程

21.0 g of 5-bromo-2-furancarboxylic acid were suspended in 650 ml of toluene and 40 ml of thionyl chloride and the suspension was heated to reflux for 2 hours. The reaction solution was thereafter concentrated, whereby 5-bromo-2-furancarboxylic acid chloride was obtained as the residue.

后处理

  1. temperatureto reflux for 2 hours
  2. concentrationThe reaction solution was thereafter concentrated

来源与证据

ORD记录
ord-374bfbb4f33346df9af44276ccb38c16
来源数据集
uspto-grants-1988_08
专利号
US04764522

反应笔记

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