吡啶-2-丙氨 → HCID 178512789，化合物

HRID 372012笔记

反应方程式

HRID 372012 反应方程式
[NH2:1][CH2:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][N:6]=1.[S:11]([O-:15])([O-:14])(=[O:13])=[O:12].CS[C:18]([NH2:20])=[NH2+:19].CSC(N)=[NH2+]>O>[S:11]([OH:15])([OH:14])(=[O:13])=[O:12].[N:6]1[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=1[CH2:4][CH2:3][CH2:2][NH:1][C:18]([NH2:20])=[NH:19]

参与物

4

反应物 2

HCID 3159614吡啶-2-丙氨HCID 6604939S-甲基异硫脲硫酸盐

产物 1

HCID 178512789HCID 178512789，化合物

试剂、催化剂与溶剂 1

HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]溶剂

实验过程

A solution of 2-(3-aminopropyl)pyridine (2.72 g) and S-methylthiouronium sulphate (2.78 g) in water (40 ml) is heated under reflux for 28 hours. The product isolated by the manner described in Example 1 was recrystallized from methanol, yielding 3-(2-pyridyl)propylguanidine sulphate, m.p. 185°-187° C.

后处理

  1. temperatureunder reflux for 28 hours
  2. customThe product isolated by the manner
  3. customwas recrystallized from methanol

来源与证据

ORD记录
ord-7f50331ed03b4f5c90002a3e7ae7bccd
来源数据集
uspto-grants-1978_05
专利号
US04088769

反应笔记

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