碘甲烷 → 3-Hydroxy-2-iodo-1,6-dimethylpyridinium iodide

HRID 416560

反应方程式

HRID 416560 反应方程式
[I:1][C:2]1[C:7]([OH:8])=[CH:6][CH:5]=[C:4]([CH3:9])[N:3]=1.[I:10][CH3:11]>>[I-:1].[OH:8][C:7]1[C:11]([I:10])=[N+:3]([CH3:2])[C:4]([CH3:9])=[CH:5][CH:6]=1

参与物

3

反应物 2

HCID 6328碘甲烷HCID 899573-羟基-2-碘-6-甲基吡啶

产物 1

HCID 222664663-Hydroxy-2-iodo-1,6-dimethylpyridinium iodide

实验过程

2-Iodo-3-hydroxy-6-methylpyridine (835 mg) and iodomethane (3 mL) were added in glass sealed cube, and the reaction mixture was reacted at 130° C. for 4 h and at 180° C. for 1 h. The reaction mixture was completely evaporated to give 3-hydroxy-2-iodo-1,6-dimethylpyridinium iodide (2-014-02) (1.42 g).

后处理

  1. customsealed cube
  2. customthe reaction mixture was reacted at 130° C. for 4 h and at 180° C. for 1 h
  3. customThe reaction mixture was completely evaporated

来源与证据

ORD记录
ord-ac5bfb723490414b8bfa5d7705e7c0c2
来源数据集
uspto-grants-2012_01
专利号
US08088924B2

关联笔记

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