海萝胶 → 3,4-bis-(4-methoxyphenyl)-5-ethyl-4H-1,2,4-triazole hydrochloride

HRID 4594

反应方程式

HRID 4594 反应方程式
[ClH:1].[CH3:2][O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[N:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)[C:13]([CH2:23][CH3:24])=[N:12][N:11]=2)=[CH:6][CH:5]=1.C(OC(C)C)(C)C>C(O)C>[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[N:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)[C:13]([CH2:23][CH3:24])=[N:12][N:11]=2)=[CH:8][CH:9]=1

参与物

5

反应物 3

HCID 313海萝胶HCID 7914异丙醚HCID 130540183,4-bis-(4-methoxyphenyl)-5-ethyl-4H-1,2,4-triazole

产物 1

HCID 201515453,4-bis-(4-methoxyphenyl)-5-ethyl-4H-1,2,4-triazole hydrochloride

试剂、催化剂与溶剂 1

HCID 702乙醇溶剂2 次

实验过程

2.9 ml of a solution of 5.9N hydrogen chloride in ethanol were aded to a solution of 5 g of the product of Example 1 in 5 ml of ethanol and the mixture was stirred while adding isopropyl ether thereto. The mixture was stirred for 24 hours and was filtered. The product was empasted with isopropyl ether, filtered and dried under pressure to obtain 4.4 g of 3,4-bis-(4-methoxyphenyl)-5-ethyl-4H-1,2,4-triazole hydrochloride.

后处理

  1. stirringThe mixture was stirred for 24 hours
  2. filtrationwas filtered
  3. filtrationfiltered
  4. customdried under pressure

来源与证据

ORD记录
ord-29c1287a74224764a2342d6da5b34f12
来源数据集
uspto-grants-1988_02
专利号
US04727084

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