乙酐 → HCID 20263934，化合物
反应方程式
[CH3:1][C:2]1[CH:7]=[C:6]([CH2:8][OH:9])[C:5]([CH2:10][OH:11])=[CH:4][N:3]=1.[C:12](OC(=O)C)(=[O:14])[CH3:13]>N1C=CC=CC=1>[CH3:1][C:2]1[CH:7]=[C:6]([CH2:8][O:9][C:12](=[O:14])[CH3:13])[C:5]([CH2:10][OH:11])=[CH:4][N:3]=1参与物
4
实验过程
2-Methyl-4,5-di(hydroxymethyl)pyridine (0.1 mole) is stirred in pyridine (50 ml.) with acetic anhydride (0.1 mole) at room temperature overnight. The pyridine is evaporated and the residue is dissolved in 10 ml. water and extracted with 2 × 30 ml. of chloroform. After drying over magnesium sulfate, the chloroform is evaporated and the residue is chromatographed on a silica gel column using benzene-ethanol as eluate. By this procedure is obtained:
后处理
- customThe pyridine is evaporated
- dissolutionthe residue is dissolved in 10 ml
- extractionwater and extracted with 2 × 30 ml
- dry with materialAfter drying over magnesium sulfate
- customthe chloroform is evaporated
- customthe residue is chromatographed on a silica gel column
- customBy this procedure is obtained
来源与证据
- ORD记录
- ord-586aa49d9763422abed1c87050daa187
- 来源数据集
- uspto-grants-1977_12
- 专利号
- US04061759
反应笔记
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