3,4-二硝基氯苯 → ethyl P-methyl-2-nitro-5-chlorophenylphosphinate

HRID 463553

反应方程式

HRID 463553 反应方程式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[C:4]([N+]([O-])=O)[CH:3]=1.[CH3:14][P:15]([O:19]CC)[O:16][CH2:17][CH3:18]>C(#N)C>[CH3:14][P:15]([C:4]1[CH:3]=[C:2]([Cl:1])[CH:7]=[CH:6][C:5]=1[N+:8]([O-:10])=[O:9])(=[O:19])[O:16][CH2:17][CH3:18]

参与物

4

反应物 2

HCID 330973,4-二硝基氯苯HCID 85063甲基二乙氧基膦

产物 1

HCID 53860251ethyl P-methyl-2-nitro-5-chlorophenylphosphinate

试剂、催化剂与溶剂 1

HCID 6342乙腈溶剂

实验过程

A mixture of 4-chloro-1,2-dinitrobenzene (3.31 mmol) and diethyl methylphosphonite (5.30 mmol) in 3 ml of acetonitrile is stirred at RT overnight. The mixture is then concentrated and the residue is purified by preparative TLC to yield ethyl P-methyl-2-nitro-5-chlorophenylphosphinate.

后处理

  1. concentrationThe mixture is then concentrated
  2. customthe residue is purified by preparative TLC

来源与证据

ORD记录
ord-d946924498814018b352a39df226c1bf
来源数据集
uspto-grants-1985_05
专利号
US04520197

关联笔记

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