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2,6-二甲氧基苯甲醛 → 6-(2,6-Dimethoxyphenyl)-1-(naphthalen-2-ylmethyl)piperidin-2-one
参与物
| 角色 | 名称 | HCID | 投料 |
|---|---|---|---|
| 反应物 | 2,6-二甲氧基苯甲醛 | HCID 96404 | — |
| 反应物 | 1-(2-萘基)甲胺 | HCID 137282 | — |
| 产物 | 6-(2,6-Dimethoxyphenyl)-1-(naphthalen-2-ylmethyl)piperidin-2-one | HCID 69082306 | — |
反应步骤
Prepared according to the described general procedure 6 (GP6) with commercially available naphthalen-2-ylmethanamine and commercially available 2,6-dimethoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions H): tR=1.35 min.; [M+H]+: 375.79 g/mol.
来源与证据
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 专利号 | US09242970B2 |
| 来源数据集 | uspto-grants-2016_01 |
| ORD ID | ord-0d1651c645b5490f981780cc2d70909e |
| 来源说明 | uspto-grants-2016_01 |