氯甲酸丙酯 → (R)-3-Propoxycarbonylamino-pyrrolidine-1-carboxylic acid adamantan-2-yl ester

参与物

反应步骤

The title compound was prepared from (R)-2-adamantyl 3-aminopyrrolidine-1-carboxylate HCl salt and propyl chloroformate following a procedure analogous to that described in Example 3 Step 2. LC-MS Method 1 tR=2.00 min, m/z=351; 1H NMR (CDCl3) 0.97 (t, 3H), 1.50-2.05 (16H), 2.19 (m, 1H), 2.42 (1H), 3.29 (dd, 1H), 3.50 (m, 2H), 3.70 (m, 1H), 4.04 (m, 2H), 4.28 (1H), 4.78 (1H), 4.83 (s, 1H)

来源与证据