N-(2-aminoethyl)-4-(1H-imidazol-1-yl)benzamide hydrochloride → N-(2-Aminoethyl)-4-(1H-imidazol-1-yl)benzamide

HRID 728811

反应方程式

HRID 728811 反应方程式
Cl.[NH2:2][CH2:3][CH2:4][NH:5][C:6](=[O:18])[C:7]1[CH:12]=[CH:11][C:10]([N:13]2[CH:17]=[CH:16][N:15]=[CH:14]2)=[CH:9][CH:8]=1>O>[NH2:2][CH2:3][CH2:4][NH:5][C:6](=[O:18])[C:7]1[CH:12]=[CH:11][C:10]([N:13]2[CH:17]=[CH:16][N:15]=[CH:14]2)=[CH:9][CH:8]=1

参与物

3

反应物 1

HCID 45259278N-(2-aminoethyl)-4-(1H-imidazol-1-yl)benzamide hydrochloride

产物 1

HCID 14664358N-(2-Aminoethyl)-4-(1H-imidazol-1-yl)benzamide

试剂、催化剂与溶剂 1

HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]溶剂

实验过程

Dissolve N-(2-aminoethyl)-4-(1H-imidazol-1-yl)benzamide hydrochloride in 50mL H2O and pour onto a column of hydroxide anion exchange resin. Flush the column with H2O and collect fractions with pH>8. Combine the basic fractions and remove the solvents in vacuo to obtain the free base.

后处理

  1. customFlush the column with H2O
  2. customcollect fractions with pH>8
  3. customremove the solvents in vacuo
  4. customto obtain the free base

来源与证据

ORD记录
ord-b5dab3118b764e1c8e15f1d41f6b4f33
来源数据集
uspto-grants-1991_09
专利号
US05051423

关联笔记

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