4-(辛氧基)苯甲酸 → 4-辛氧基苯甲酰氯

HRID 751笔记

反应方程式

HRID 751 反应方程式
S(Cl)([Cl:3])=O.[CH2:5]([O:13][C:14]1[CH:22]=[CH:21][C:17]([C:18](O)=[O:19])=[CH:16][CH:15]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]>>[CH2:5]([O:13][C:14]1[CH:22]=[CH:21][C:17]([C:18]([Cl:3])=[O:19])=[CH:16][CH:15]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

参与物

3

反应物 2

HCID 172314-(辛氧基)苯甲酸2 次HCID 24386氯化亚砜

产物 1

HCID 27602504-辛氧基苯甲酰氯

实验过程

A large excess of thionyl chloride was added to 10 g of the p-octyloxybenzoic acid prepared in (1), and the mixture was refluxed for 5 hours. Excessive thionyl chloride was distilled off to give a crude end compound.

后处理

  1. temperaturethe mixture was refluxed for 5 hours
  2. distillationExcessive thionyl chloride was distilled off
  3. customto give a crude end compound

来源与证据

ORD记录
ord-89aff4b1c18042e4bbb1f88ebba96f86
来源数据集
uspto-grants-1998_03
专利号
US05723069

反应笔记

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