化工社化工社化学信息打印报告 · 仅供科研参考
氯化亚砜 → HCID 66937557，化合物
参与物
| 角色 | 名称 | HCID | 投料 |
|---|---|---|---|
| 反应物 | 氯化亚砜 | HCID 24386 | — |
| 反应物 | 1,5-二甲基-1H-吡唑-3-甲醇 | HCID 2776366 | — |
| 溶剂 | 二氯甲烷 | HCID 6344 | — |
| 产物 | HCID 66937557 | HCID 66937557 | 101.8% |
反应步骤
To (1,5-dimethyl-1H-pyrazol-3-yl)methanol (5.01 g, 39.71 mmol) in DCM (80 mL) at 0° C. was cautiously added thionyl chloride (25 mL, 343.6 mmol). The cold bath was removed and the reaction mixture was stirred at ambient temperature for 3 hours. The reaction mixture was concentrated under reduced pressure to give crude product (7.32 g).
来源与证据
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 专利号 | US08841455B2 |
| 来源数据集 | uspto-grants-2014_09 |
| ORD ID | ord-a0e28097d0434a88bd9c842f43cfe4a0 |
| 来源说明 | uspto-grants-2014_09 |