2,4,6-三甲基苯磺酰氯 → 1-(Mesitylsulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride

参与物

角色	名称	HCID	投料
反应物	2,4,6-三甲基苯磺酰氯	HCID 13046	—
反应物	1-(1-叔丁氧羰基)-4-(4-吲哚基)哌嗪	HCID 22015386	—
产物	1-(Mesitylsulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride	HCID 10295599	—

反应步骤

The title compound was prepared from 4-(4-boc-piperazinyl)-indole and mesitylsulfonylchloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.10 (br, 1 H), 7.71 (d, J=5 Hz, 1 H), 7.40–7.20 (m, 3 H), 7.00–6.80 (m, 2 H), 6.51 (d, J=8 Hz, 1 H), 3.30–3.20 (m, 8 H), 2.41 (s, 6 H), 2.27 (s, 3 H); MS (ESI+) for m/z 384 (M+H)+.

来源与证据

DOI	10.6084/m9.figshare.5104873.v1
专利号	US07087750B2
来源数据集	uspto-grants-2006_08
ORD ID	ord-d34fb486e4584bdcb5636a56b735f851
来源说明	uspto-grants-2006_08