溴化苄 → Tert-butyl 1-benzyl-2-oxo-8-(2-oxopyrrolidin-1-yl)-1,2,3,4-tetrahydroquinolin-3-ylcarbamate

反应方程式

[Br:1][CH2:2][c:3]1[cH:4][cH:5][s:6][cH:7]1.[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[Br:15].[O:16]=[C:17]1[NH:18][c:19]2[c:20]([N:35]3[C:36](=[O:40])[CH2:37][CH2:38][CH2:39]3)[cH:21][cH:22][cH:23][c:24]2[CH2:25][CH:26]1[NH:27][C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34]>>[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[N:18]1[C:17](=[O:16])[CH:26]([NH:27][C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[CH2:25][c:24]2[c:19]1[c:20]([N:35]1[C:36](=[O:40])[CH2:37][CH2:38][CH2:39]1)[cH:21][cH:22][cH:23]2

参与物

反应物 3

HCID 7498溴化苄

HCID 5207033-溴甲基噻吩

HCID 59620362Tert-butyl 2-oxo-8-(2-oxopyrrolidin-1-yl)-1,2,3,4-tetrahydroquinolin-3-ylcarbamate

产物 1

HCID 59620395Tert-butyl 1-benzyl-2-oxo-8-(2-oxopyrrolidin-1-yl)-1,2,3,4-tetrahydroquinolin-3-ylcarbamate

来源与证据

ORD记录: ord-451c3910ce084a4ebc5695d4eef574c5
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反应笔记

加载中…