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氢氧化锂 → 6-((4-Fluorophenyl)(hydroxy)methyl)picolinic acid
参与物
| 角色 | 名称 | HCID | 投料 |
|---|---|---|---|
| 反应物 | 氢氧化锂 | HCID 3939 | — |
| 反应物 | Methyl 6-((4-fluorophenyl)(hydroxy)methyl)picolinate | HCID 71087862 | — |
| 产物 | 6-((4-Fluorophenyl)(hydroxy)methyl)picolinic acid | HCID 71087341 | — |
反应步骤
In analogy to the procedure described in Example 5 c), methyl 6-((4-fluorophenyl)(hydroxy)methyl)picolinate was saponified with lithium hydroxide to obtain the title compound. MS (EI): m/e=246.1 [M−H]−.
来源与证据
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 专利号 | US09290451B2 |
| 来源数据集 | uspto-grants-2016_03 |
| ORD ID | ord-f9d5954f8d1d4d4784463f615aa67ea6 |
| 来源说明 | uspto-grants-2016_03 |