氯化铵 → HCID 20309577，化合物

HRID 972773笔记

反应方程式

HRID 972773 反应方程式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]([F:12])([F:11])[F:10])=[CH:5][C:4]=1[Li].[CH3:14][N:15]1[C:19](=[O:20])[CH2:18][CH2:17][C:16]1=[O:21].[Cl-].[NH4+]>CCOCC.C1C=CC=CC=1>[CH3:14][NH:15][C:16](=[O:21])[CH2:17][CH2:18][C:19](=[O:20])[C:4]1[CH:5]=[C:6]([C:9]([F:12])([F:11])[F:10])[CH:7]=[CH:8][C:3]=1[O:2][CH3:1]

参与物

6

反应物 3

HCID 25517氯化铵HCID 70717N-甲基丁二酰胺HCID 178506727HCID 178506727，化合物

产物 1

HCID 20309577HCID 20309577，化合物

试剂、催化剂与溶剂 2

HCID 241Benzene溶剂HCID 3283乙醚溶剂

实验过程

A solution of 2-methoxy-5-trifluoromethylphenyllithium in ether was added to a cold stirred solution of N-methylsuccinimide in benzene. The resultant mixture was allowed to stand overnight and was then decomposed with ammonium chloride solution to give N-methyl 3-(2-methoxy-5-trifluoromethylbenzoyl)propionamide.

来源与证据

ORD记录
ord-90a728e6d4d341cba992ebe447adf4a2
来源数据集
uspto-grants-1977_10
专利号
US04053601

反应笔记

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