HCID114705

(+)-Styrene oxide

(2R)-2-phenyloxirane

C8H8O120.15 g/molCAS 20780-53-4

查看相关反应子结构检索查找相似结构

IDENTITY

结构与身份

标准SMILES: c1ccc([C@@H]2CO2)cc1
InChIKey: AWMVMTVKBNGEAK-QMMMGPOBSA-N
分子式: C8H8O
平均分子量: 120.15 g/mol
单同位素质量: 120.05751487

COMPUTED

结构计算性质

已同步

XLogP: 1.6
极性表面积: 12.5 Å²
氢键供体: 0
氢键受体: 1
可旋转键: 1
重原子: 9
形式电荷: 0
复杂度: 94

GHS

GHS分类

GHS Classification

Danger

H312 (98.2%): Harmful in contact with skin [Warning Acute toxicity, dermal]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H350 (100%): May cause cancer [Danger Carcinogenicity]

P203, P264+P265, P280, P302+P352, P305+P351+P338, P317, P318, P321, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 57 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

HAZARDS

危害信息

Regulatory Information

Chemical: Oxirane, phenyl-, (R)-

(R)-Styrene oxide: Does not have an individual approval but may be used under an appropriate group standard

Other Safety Information

IMAP assessments - Phenyloxirane and its isomers: Human health tier II assessment

Hazard Classes and Categories

Acute Tox. 4 (98.2%)；Eye Irrit. 2 (100%)；Carc. 1B (100%)

Acute toxicity - category 4；Eye irritation - category 2A；Skin sensitisation - category 1；Carcinogenicity - category 1B

REGULATORY

法规信息

Regulatory Information

Chemical: Oxirane, phenyl-, (R)-

(R)-Styrene oxide: Does not have an individual approval but may be used under an appropriate group standard

PHARMACOLOGY

药理信息

MeSH Pharmacological Classification

Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.

Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.

ALIASES

名称与别名

共 63 条

(R)-Styrene oxide20780-53-4(2R)-2-phenyloxiraneR-Phenyloxirane(R)-(+)-Styrene oxideR-STYRENE OXIDE(R)-(Epoxyethyl)benzeneOxirane, phenyl-, (2R)-Styrene oxide, (R)-0HB27D5MRWCHEBI:45389DTXSID401349483(+)-styrene oxideRefChem:889336DTXCID701778495606-637-6(R)-2-phenyloxirane(R)-PhenyloxiraneOxirane, 2-phenyl-, (2R)-MFCD00066210

REACTIONS