HCID9811564

Bis(dibenzylideneacetone)palladium

tris((1E,4E)-1,5-diphenylpenta-1,4-dien-3-one);bis(palladium)

C51H42O3Pd2915.7 g/molCAS 51364-51-3

查看相关反应子结构检索查找相似结构

IDENTITY

结构与身份

标准 SMILES: O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.[Pd].[Pd]
InChIKey: CYPYTURSJDMMMP-WVCUSYJESA-N
分子式: C51H42O3Pd2
平均分子量: 915.7 g/mol
单同位素质量: 914.12036

COMPUTED

结构计算性质

已同步

极性表面积: 51.2 Å²
氢键供体: 0
氢键受体: 3
可旋转键: 12
重原子: 56
形式电荷: 0
复杂度: 272

TOXICITY

毒理信息

来源：PubChem

Health Effects

Contact with palladium may cause palladium sensitivity and allergy. Animal studies have shown that palladium may damage the liver and kidney. (L798)

Toxicity Summary

Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, and interact with functional groups of macromolecules, such as proteins or DNA. Palladium complexes binding to DNA and RNA leads to strand breakage. Palladium ions are able to inhibit most major cellular functions, including DNA and RNA synthesis. Palladium compounds have been shown to bind to and inhibit various enzymes, including creatine kinase and prolyl hydroxylase. (L798)

Signs and Symptoms

Skin contact with palladium may cause contact dermatitis, erythema, and oedema. (L798)

Carcinogen Classification

No indication of carcinogenicity to humans (not listed by IARC).

PHARMACOLOGY

药理信息

来源：PubChem

Metabolism/Metabolites

Palladium may be absorbed through oral, dermal, and inhalation exposure. Once in the body it distributes to the kidney, liver, spleen, lymph nodes, adrenal gland, lung and bone. Palladium's ability to form complexes allows it the bind to amino acids, proteins, DNA, and other macromolecules. Palladium and its metabolites are excreted in the urine and faeces. (A21)

ALIASES

名称与别名

共 91 条

Bis(dibenzylideneacetone)palladiumRefChem:56904551364-51-3Tris(dibenzylideneacetone)dipalladium(0)tris(dibenzylideneacetone)dipalladiumpd2(dba)360748-47-2Pd2dba3MFCD00013310Tris(Dibenzylideneacetone)dipalladium (0)TRIS(DIBENZYLIDENEACETONYL)BIS-PALLADIUMTRIS DBAtris(dibenzylideneacetone) dipalladium(0)tris((1E,4E)-1,5-diphenylpenta-1,4-dien-3-one) dipalladiumtris[dibenzylideneacetone]dipalladium (0)tris-(dibenzylideneacetone)dipalladiumC51H42O3Pd2Tris(dibezylideneacetone)dipalladiumPd2 dba3tris(dibenzylideneacetone)dipalladium (o)

REACTIONS