3-Pyridylamin
3-Aminopyridine
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Grundinformationen
- CAS
462-08-8- Standard-SMILES
Nc1cccnc1- InChIKey
CUYKNJBYIJFRCU-UHFFFAOYSA-N- Summenformel
- C5H6N2
- Durchschnittliche Molmasse
- 94,11 g/mol
- Monoisotopische Masse
- 94,05309819
Überblick
RN given refers to parent cpd
Namen und Bezeichner
- Bevorzugter Name
- 3-Aminopyridine
- IUPAC
- pyridin-3-amine
- Lokaler Name
- 3-Pyridylamin
- Englischer Name
- 3-Aminopyridine
- Summenformel
- C5H6N2
- Molmasse
- 94.11
Namen und Synonyme
3-AMINOPYRIDINE462-08-83-Pyridinaminem-Aminopyridinebeta-AminopyridineDTXSID9047461UN267169JE8P2L84NSC-15040DTXCID7027461UN-2671RefChem:911164
Weitere Namen anzeigen
462-08-0462-08-03APYNSC 15040AKOS 909773-Pyridylamin
207-322-2pyridin-3-amine3-PyridylamineAmino-3 pyridinePyridine, 3-amino-3-amino pyridinepyridin-3-ylamine.beta.-Aminopyridine
Datenbank-Bezeichner
- CAS
462-08-8- PubChem CID
- 10009
- DTXSID
DTXSID9047461- ChEMBL
CHEMBL25541- UNII
- 69JE8P2L84
- EC Number
- 207-322-2
- Nikkaji
- J1.535K
Eigenschaften
Berechnete StruktureigenschaftenWird ergänzt
- XLogP
- 0,1
- Polarare Oberfläche (TPSA)
- 38,9 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 7
- Formalladung
- 0
- Komplexität
- 54
Experimentelle und physikochemische Eigenschaften
Chemical ClassesNitrogen Compounds -> Pyridines
SpringerMaterials PropertiesMolecular structure
LogP0.05
Flash Point190.4 °F
Boiling Point483.8 °F
Melting Point147.2 °F
Vapor Pressure0.43 [mmHg]
Physical Description
Other Solid
Solid; [Merck Index] Brown solid; [NTP] White to light brown solid with an unpleasant odor; [OSHA] Brown crystalline solid; [Alfa Aesar MSDS]
White to yellow-brown crystals with an unpleasant odor.
Ionization Efficiency
Positive
3.09
2.7
Agilent XCT
Electrospray ionization
formic acid (5.3nM)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H300 (15%): Fatal if swallowed [Danger Acute toxicity, oral]
P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 60 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: 3-Pyridinamine
3-Pyridinamine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 3-Pyridinamine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 29-07-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/16757
3-Aminopyridine: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Causes convulsions in intracerebral lethal-dose studies of mice; Intravenous LD50 (mouse) = 24 mg/kg; [RTECS] Readily absorbed through skin; [NTP] A skin, eye, and mucous membrane irritant; Toxic by ingestion; [ToxPlanet: OSHA] A skin and strong eye irritant; Harmful by skin absorption; Toxic by ingestion; Oral LD50 (rat) = 50-200 mg/kg; [Alfa Aesar MSDS] See 2-Aminopyridine.
Hazard Classes and CategoriesAcute Tox. 2 (15%)
Toxikologische Informationen
Chemie und Industrie
Verwendung und Herstellung
UsesUsed to make pharmaceuticals and dyes; [Merck Index] Also used to make agrochemicals and as a plant growth regulator; [NTP]
U.S. Production2023: 250,000 - <550,000 lb
Industry UsesIntermediate
General Manufacturing Information
All Other Basic Organic Chemical Manufacturing
3-Pyridinamine: ACTIVE
Anwendungen
Verwenden3-Aminopyridine is a monosubstituted pyridine that shows convulsive effects on cortical Neurons. 3-Aminopyridine is used in the synthesis of of organic ligand 3-Pyridylnicotinamide. 3-Aminopyridine al ong with other aminopyridines have been shown to reversibly block voltage-dependent potassium channels,
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