Methallenestril

Ercostrol · Vallestril · Novestrine · methallenestril · methallenestril USP/EP/BP · 3-(6-methoxy-2-naphthyl)-2,2-dimethyl-valeric acid · 3-(6-methoxynaphthalen-2-yl)-2,2-dimethylpentanoic acid · 3-(6-methoxynaphthalen-2-yl)-2,2-dimethyl-pentanoic acid

https://huagongshe.com/de/chemical/10599

Identifikatoren & physikalische Daten

CAS No.	15372-35-7
Summenformel	C18H22O3
Durchschnittliche Molmasse	286,4 g/mol
Monoisotopische Masse	286,15689456 g/mol
SMILES	CCC(c1ccc2cc(OC)ccc2c1)C(C)(C)C(=O)O
InChIKey	KHLJKRBMZVNZOC-UHFFFAOYSA-N
PubChem CID	10599
ChEMBL	CHEMBL1697842
ChEBI	CHEBI:6808
EC No.	208-232-6
DTXSID	DTXSID7023275
Lokaler Name	Methallenestril

Chemische & physikalische Eigenschaften

XLogP	4,7
Polarare Oberfläche (TPSA)	46,5
H-Brücken-Donoren	1
H-Brücken-Akzeptoren	3
Frei drehbare Bindungen	5
Schwere Atome	21
Formalladung	0
Komplexität	363
Color/Form	CRYSTALS FROM DIL METHANOL
Löslichkeit	SOL IN ETHER & VEGETABLE OILSINSOL IN WATERFREELY SOL IN CHLOROFORM
Schmelzpunkt	139-140 °C139-140°
Siedepunkt	437.0±20.0 °C(Predicted)
Dichte	1.108±0.06 g/cm3(Predicted)
pKa (Säurekonstante)	4.88±0.50(Predicted)

Sicherheit & Vorschriften

Human Toxicity Excerpts	BREAST ENLARGEMENT & NODULARITY OCCURRED IN BOTH MALE & FEMALE CHILDREN AFTER CONSUMPTION OF VITAMIN CAPSULES CONTAMINATED WITH ESTROGENS. /ESTROGEN/MALAISE, IRRITABILITY, & DEPRESSION...OCCUR WITH SMALL DOSES &...WITH LARGE DOSES. EFFECT ON LIBIDO IS ERRATIC, BEING INCR IN SOME & DECR IN OTHERS. ... CHANGES IN CONCN OF SOME OF CLOTTING FACTORS IN BLOOD...INCR INCIDENCE OF THROMBOPHLEBITIS & THROMBOEMBOLISM IN...SUPERFICIAL & DEEP VEINS. /ESTROGENS/PULMONARY EMBOLISM, CEREBRAL EMBOLISM WITH STROKE & MESENTERIC VASCULAR OCCULSION OCCUR. CORONARY THROMBOSIS...INCR... ALTER HEPATIC FUNCTION, WHICH... ALTER...TESTS OF LIVER FUNCTION AS WELL AS VARIOUS SYNTHETIC & BIOTRANSFORMATION PROCESSES. ...DECR IN GLUCOSE TOLERANCE, & DIABETES MELLITUS MAY BE EXACERBATED. /ESTROGENS/SERUM TRIGLYCERIDES RISE, &...HYPERLIPIDEMIA MAY OCCUR... COMPOSITION IS ALTERED...INCR OF GALL STONES... PORPHYRIA MAY BE PROVOKED. CHANGES IN CONCN OF BLOOD PROTEINS MAY OCCURTHYROXINE- & GLUCOCORTICOID-BINDING PROTEINS ARE INCR, WHICH MAY ALTER ENDOCRINE RELATIONSHIPS. /ESTROGENS/For more Human Toxicity Excerpts (Complete) data for METHALLENESTRIL (10 total), please visit the HSDB record page.
Gefahrstoffdaten	517-18-0(Hazardous Substances Data)

Human Toxicity Excerpts

BREAST ENLARGEMENT & NODULARITY OCCURRED IN BOTH MALE & FEMALE CHILDREN AFTER CONSUMPTION OF VITAMIN CAPSULES CONTAMINATED WITH ESTROGENS. /ESTROGEN/MALAISE, IRRITABILITY, & DEPRESSION...OCCUR WITH SMALL DOSES &...WITH LARGE DOSES. EFFECT ON LIBIDO IS ERRATIC, BEING INCR IN SOME & DECR IN OTHERS. ... CHANGES IN CONCN OF SOME OF CLOTTING FACTORS IN BLOOD...INCR INCIDENCE OF THROMBOPHLEBITIS & THROMBOEMBOLISM IN...SUPERFICIAL & DEEP VEINS. /ESTROGENS/PULMONARY EMBOLISM, CEREBRAL EMBOLISM WITH STROKE & MESENTERIC VASCULAR OCCULSION OCCUR. CORONARY THROMBOSIS...INCR... ALTER HEPATIC FUNCTION, WHICH... ALTER...TESTS OF LIVER FUNCTION AS WELL AS VARIOUS SYNTHETIC & BIOTRANSFORMATION PROCESSES. ...DECR IN GLUCOSE TOLERANCE, & DIABETES MELLITUS MAY BE EXACERBATED. /ESTROGENS/SERUM TRIGLYCERIDES RISE, &...HYPERLIPIDEMIA MAY OCCUR... COMPOSITION IS ALTERED...INCR OF GALL STONES... PORPHYRIA MAY BE PROVOKED. CHANGES IN CONCN OF BLOOD PROTEINS MAY OCCURTHYROXINE- & GLUCOCORTICOID-BINDING PROTEINS ARE INCR, WHICH MAY ALTER ENDOCRINE RELATIONSHIPS. /ESTROGENS/For more Human Toxicity Excerpts (Complete) data for METHALLENESTRIL (10 total), please visit the HSDB record page.

Gefahrstoffdaten

517-18-0(Hazardous Substances Data)

Anwendungen & Verwendung

Verwenden

Medicine (estrogen).