N-(N-Glycylglycyl)glycin

Glycylglycylglycine

HCID 11161

Teilstruktursuche Ähnliche Strukturen suchen

Grundinformationen

CAS: 556-33-2
Standard-SMILES: NCC(=O)NCC(=O)NCC(=O)O
InChIKey: XKUKSGPZAADMRA-UHFFFAOYSA-N
Summenformel: C6H11N3O4
Durchschnittliche Molmasse: 189,17 g/mol
Monoisotopische Masse: 189,07495583

Überblick

Glycyl-glycyl-glycine is a tripeptide in which three glycine units are linked via peptide bonds in a linear sequence. It is a tautomer of a Gly-Gly-Gly zwitterion.

Namen und Bezeichner

Bevorzugter Name: Glycylglycylglycine
IUPAC: 2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetic acid
Lokaler Name: N-(N-Glycylglycyl)glycin
Englischer Name: Glycyl-glycyl-glycine
Summenformel: C6H11N3O4
Molmasse: 189.17

Namen und Synonyme

556-33-2GlycylglycylglycineGlycyl-glycyl-glycineTriglycineGly-Gly-Gly2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetic acidCVK73ZDQ8BNSC-46707CHEBI:63961DTXSID802041402-((2-((2-aminoacetyl)amino)acetyl)amino)acetic acid2-({2-[(2-AMINOACETYL)AMINO]ACETYL}AMINO)ACETIC ACID

Weitere Namen anzeigen

Gly-Gly-Gly-OHL-GLYCYL-GLYCYL-GLYCINEH2N-GGG-OHTripeptide-443-mer polyGlyTriglycine,99%

diglycyl-glycineGGG peptideRefChem:143968DTXCID801266312-((2-((2-azaniumylacetyl)amino)acetyl)amino)acetate209-122-0H-Gly-Gly-Gly-OHDiglycylglycine

Datenbank-Bezeichner

CAS: 556-33-2
PubChem CID: 11161
DTXSID: DTXSID80204140
ChEMBL: CHEMBL54278
ChEBI: CHEBI:63961
UNII: CVK73ZDQ8B
EC Number: 209-122-0
Nikkaji: J43.163J

Eigenschaften

Berechnete Struktureigenschaften

XLogP: -3,6
Polarare Oberfläche (TPSA): 122 Å²
H-Brücken-Donoren: 4
H-Brücken-Akzeptoren: 5
Frei drehbare Bindungen: 5
Schwere Atome: 13
Formalladung: 0
Komplexität: 216

Experimentelle und physikochemische Eigenschaften

Chemical ClassesBiological Agents -> Amino Acids and Derivatives

LogP-2.68

Solubility58.5 mg/mL at 25 °C

Melting Point246 °C

Physical Description · 2 Einträge

Crystals; [Alfa Aesar MSDS]

Solid

Dissociation Constants · 2 Einträge

3.23

7.94

Physikochemische Eigenschaften

Schmelzpunkt: 240 · 240-250 °C
Siedepunkt: 324.41 °C · 324.41°C (rough estimate)
Dichte: 1.4204 · 1.4204 (rough estimate)
Brechungsindex: 1.525 · 1.5250 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit: 2 O: · H2O: 0.5 M at 20 °C, clear, colorless
Aggregatzustand: Solid
pka: 3.225 · 3.225(at 25℃)
Farbe: White to Off-White
PH: 4.5 · 4.5-6.0 (25℃, 0.5M in H2O)
Wasserlöslichkeit: Soluble in water (94.6 mg/ml at 20°C), methanol (50 mg/ml), and 80% acetic acid (50 mg/ml).
Merck: 14 · 14,6579
BRN: 1711130 · 1711130
InChI: 1S/C6H11N3O4/c7-1-4(10)8-2-5(11)9-3-6(12)13/h1-3,7H2,(H,8,10)(H,9,11)(H,12,13)
InChIKey: XKUKSGPZAADMRA-UHFFFAOYSA-N
SMILES: NCC(=O)NCC(=O)NCC(O)=O
CAS Datenbank: 556 · 556-33-2(CAS DataBase Reference)
NIST chemische Informationen: N-(N-Glycylglycyl)glycine(556-33-2)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.

Danger

H314 (33.3%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P261, P264, P264+P265, P271, P272, P273, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Hazards SummaryMay cause irritation; [Alfa Aesar MSDS]

Hazard Classes and CategoriesSkin Corr. 1B (33.3%)

Sicherheitsdaten

F: 3-10
wgk: 3
hs_code: 29241990
Speicherklasse: 11 - Combustible Solids

Chemie und Industrie

Pharmakologische Informationen

Cellular LocationsCytoplasm

Anwendungen

VerwendenGlycyl-glycyl-glycine is used as a model peptide for studies of physicochemical parameters and molecular associations of small peptides. It is also used as a copper chelator and Substrate for tripeptide aminopeptidase.

Vor- und nachgelagerte Produkte

Nachgelagerte Produkte

Boc-Gly-Gly-Gly-OH

Anbieter100 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

T&W GROUP021-61551611 13296011611 · [email protected]

Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]

上海将来实业股份有限公司400-0066400 13621662912 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: Glycyl-glycyl-glycine is a tripeptide in which three glycine units are linked via peptide bonds in a linear sequence. It is a tautomer of a Gly-Gly-Gly zwitterion.