HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-(N-Glycylglycyl)glycin
GLY-GLY-GLY · H-GLY-GLY-GLY-OH · Gly-Gly-Gly-OH · L-GLYCYL-GLYCYL-GLYCINE · 2-[[2-[(2-Aminoacetyl)amino]acetyl]amino]acetic acid · H2N-GGG-OH · Tripeptide-44 · 3-mer polyGly
Identifikatoren & physikalische Daten
| CAS No. | 556-33-2 |
|---|---|
| Summenformel | C6H11N3O4 |
| Durchschnittliche Molmasse | 189,17 g/mol |
| Monoisotopische Masse | 189,07495583 g/mol |
| SMILES | NCC(=O)NCC(=O)NCC(=O)O |
| InChIKey | XKUKSGPZAADMRA-UHFFFAOYSA-N |
| PubChem CID | 11161 |
| ChEMBL | CHEMBL54278 |
| ChEBI | CHEBI:63961 |
| EC No. | 209-122-0 |
| DTXSID | DTXSID80204140 |
| Lokaler Name | N-(N-Glycylglycyl)glycin |
Chemische & physikalische Eigenschaften
| XLogP | -3,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 122 |
| H-Brücken-Donoren | 4 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 5 |
| Schwere Atome | 13 |
| Formalladung | 0 |
| Komplexität | 216 |
| Stoffklassen | Biological Agents -> Amino Acids and Derivatives |
| LogP (Verteilungskoeffizient) | -2.68 |
| Löslichkeit | 58.5 mg/mL at 25 °CH2O: 0.5 M at 20 °C, clear, colorlessSoluble in water (94.6 mg/ml at 20°C), methanol (50 mg/ml), and 80% acetic acid (50 mg/ml). |
| Schmelzpunkt | 246 °C240-250 °C |
| Physical Description | Crystals[Alfa Aesar MSDS]Solid |
| Dissociation Constants | 3.237.94 |
| Siedepunkt | 324.41°C (rough estimate) |
| Dichte | 1.4204 (rough estimate) |
| Brechungsindex | 1.5250 (estimate) |
| Lagerbedingungen | Keep in dark place,Sealed in dry,Room Temperature |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 3.225(at 25℃) |
| Farbe | White to Off-White |
| pH | 4.5-6.0 (25℃, 0.5M in H2O) |
| Merck | 14,6579 |
| BRN | 1711130 |
| InChI | 1S/C6H11N3O4/c7-1-4(10)8-2-5(11)9-3-6(12)13/h1-3,7H2,(H,8,10)(H,9,11)(H,12,13) |
| InChIKey | XKUKSGPZAADMRA-UHFFFAOYSA-N |
| SMILES | NCC(=O)NCC(=O)NCC(O)=O |
| CAS Datenbank | 556-33-2(CAS DataBase Reference) |
| NIST chemische Informationen | N-(N-Glycylglycyl)glycine(556-33-2) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.DangerH314 (33.3%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]P260, P261, P264, P264+P265, P271, P272, P273, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Gefahrenübersicht | May cause irritation[Alfa Aesar MSDS] |
| Hazard Classes and Categories | Skin Corr. 1B (33.3%) |
| F | 3-10 |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29241990 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
Glycyl-glycyl-glycine is used as a model peptide for studies of physicochemical parameters and molecular associations of small peptides. It is also used as a copper chelator and Substrate for tripeptide aminopeptidase.