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Silberacetat

Silver acetate

HCID 11246
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Grundinformationen

CAS
563-63-3
Standard-SMILES
CC(=O)[O-].[Ag+]
InChIKey
CQLFBEKRDQMJLZ-UHFFFAOYSA-M
Summenformel
AgC2H3O2
Durchschnittliche Molmasse
166,91 g/mol
Monoisotopische Masse
165,9184

Überblick

Silver acetate is a white crystalline plates. Light sensitive. Density 3.26 g / cm3.

Namen und Bezeichner

Bevorzugter Name
Silver acetate
IUPAC
silver acetate
Lokaler Name
Silberacetat
Englischer Name
Silver acetate
Summenformel
C2H3AgO2
Molmasse
166.91

Namen und Synonyme

Silver acetate563-63-3Silver(I) acetateSilver(1+) acetateSilver monoacetateACETIC ACID, SILVER(1+) SALT19PPS85F9HDTXSID8032041NSC-112212RefChem:183021DTXCID6012041209-254-9
Weitere Namen anzeigen
AgOAcsilver acetate, anhydrousver acetateSilver acetatAcetoxysilver(I)Silveracetate,99%silver(1+)acetatesilvermonoacetate
argentio acetatesilver;acetateAcetic acid silver saltAcetic acid, silver(1+) salt (1:1)Acetic acid silver(I) saltSilver acetate Ag(OAc)Argentous acetate; Silver Monoacetate;MFCD00012446

Datenbank-Bezeichner

CAS
563-63-3
PubChem CID
11246
DTXSID
DTXSID8032041
ChEMBL
CHEMBL4464576
UNII
19PPS85F9H
EC Number
209-254-9
Nikkaji
J43.267I

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
40,1 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
0
Schwere Atome
5
Formalladung
0
Komplexität
25,5

Experimentelle und physikochemische Eigenschaften

Chemical ClassesMetals -> Organic Acids, Metal Salts
Density3.26 at 68 °F (USCG, 1999) - Denser than water; will sink
Physical Description · 3 Einträge

Silver acetate is a white crystalline plates. Light sensitive. Density 3.26 g / cm3.

Liquid; Other Solid

White to slightly gray solid; Soluble in 100 parts cold water; [Merck Index] Solubility in water = 10 g/L; [ChemIDplus] Beige powder; [Aldrich MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
93 · decomposes [STR93]
Dichte
3.25 · 3.25
storage temp.
30 °C · Store below +30°C.
Löslichkeit
10.2 g/l · 10.2g/l
Aggregatzustand
Powder/Solid
Farbe
White to gray
Wichte
3.259 · 3.259
Wasserlöslichkeit
10.2 g/L · 10.2 g/L (20 ºC)

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 57 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: Acetic acid, silver(1+) salt

Acetic acid, silver(1+) salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, silver(1+) salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Silver acetate: Does not have an individual approval but may be used under an appropriate group standard

Health HazardsInhalation of dust irritates nose and throat. Contact with eyes or skin causes irritation. If continued for a long period, ingestion or inhalation of silver compounds can cause permanent discoloration of skin (argyria). (USCG, 1999)
Hazards Summary · 1 Eintrag

Sensitive to light; [Merck Index] No evidence of developmental toxicity or teratogenicity in rats dosed by gavage on gestation days 6-19 (even at doses maternally toxic); NOAEL for maternal toxicity was 10 mg/kg/day and 100 mg/kg/day for developmental toxicity; [NTP] Dust is irritating to eyes, nose, and throat; Solid irritates skin and eyes; [CHRIS] Caused effects to metabolism and plasma proteins in 4-day intermittent study of rats (641 mg/kg); [RTECS] A skin and strong eye irritant; May cause argyria; [Aldrich MSDS] See Silver.

Chemie und Industrie

Pharmakologische Informationen

Metabolism/Metabolites · 1 Eintrag

Silver and its compounds can be absorbed via inhalation, while silver compounds can also be absorbed orally and dermally. It distributes throughout the body in the blood, particularily to the liver. Insoluble silver salts are transformed into soluble silver sulfide albuminates, bind to amino or carboxyl groups in RNA, DNA, and proteins, or are reduced to metallic silver by ascorbic acid or catecholamines. Metallic silver is oxidized and may deposit in the tissues, causing arygria. Silver is eliminated primarily in the faeces. (L808)

Verwendung und Herstellung

Uses · 2 Einträge

Used in liquid ammonia (oxidizing agent); [Merck Index] Used in anti-smoking remedies; [EPA REDs] Used as a laboratory reagent and oxidizing agent; [Hawley]

Silver acetate is commonly used as a pesticide. It also produces a repulsive taste when combined with cigarette smoke, so it is used in chewing gum and lozenges to aid the cessation of smoking. (L813)

U.S. Production2023: 37,447 lb
Consumer UsesProcessing aids not otherwise specified
Industry UsesProcessing aids not otherwise specified
General Manufacturing Information · 2 Einträge

All Other Chemical Product and Preparation Manufacturing

Acetic acid, silver(1+) salt (1:1): ACTIVE

Anwendungen · 2 Einträge

BeschreibungSilver acetate is an organic compound with the empirical formula CH3COOAg (or AgC2H3O2). It is a photosensitive, white crystalline solid. It is a useful reagent in the laboratory as a water soluble source of silver lacking an oxidizing anion. It has been used in some antismoking drugs.

Zugehörige Reaktionen

149
Reaktionsaufzeichnung erstellen
Reaktionsgleichung von HRID 4281
HRID 4281als Katalysatoruspto-grants-1988_02
Reaktionsgleichung von HRID 5392
HRID 5392als Katalysatoruspto-grants-1993_09
Reaktionsgleichung von HRID 21964
HRID 21964als Katalysatoruspto-grants-1995_06
Reaktionsgleichung von HRID 26267
HRID 26267als Katalysatoruspto-grants-1979_04
Reaktionsgleichung von HRID 36039
HRID 36039als Katalysatoruspto-grants-1995_05
Reaktionsgleichung von HRID 66400
HRID 66400als Katalysatoruspto-grants-1978_12
Reaktionsgleichung von HRID 67028
HRID 67028als Katalysatoruspto-grants-1982_08
Reaktionsgleichung von HRID 233062
HRID 233062als Katalysatoruspto-grants-1997_01
Seite 1 von 19

Notizen zur Verbindung

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Merck
14 · 14,8505
BRN
3595636 · 3595636
Stabilität
Stable, but light sensitive. Incompatible with strong reducing agents.
InChI
1S/C2H4O2.Ag/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1
InChIKey
CQLFBEKRDQMJLZ-UHFFFAOYSA-M
SMILES
CC(O[Ag])=O
CAS Datenbank
563 · 563-63-3(CAS DataBase Reference)
NIST chemische Informationen
Silver acetate(563-63-3)
EPA chemische Informationen
Silver acetate (563-63-3)
Reactive GroupSalts, Basic
Reactivity ProfileSILVER ACETATE is freely soluble in dilute nitric acid [Merck]. Can serve as an oxidizing agent.
Air and Water ReactionsSlightly soluble in water.
Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Sicherheit und Schutzausrüstung

First AidINHALATION: move to fresh air.
Exposure Control and Personal Protection0.01 [mg/m3], inhalable fraction, as Ag (salts)[German Research Foundation (DFG)]
Threshold Limit Values (TLV)0.01 [mg/m3], as Ag (sol. compds.)
Permissible Exposure Limit (PEL)0.01 [mg/m3], as Ag (sol. compds.)
Personal Protective Equipment (PPE)Dust mask; goggles or face shield; protective gloves (USCG, 1999)
Immediately Dangerous to Life or Health (IDLH) · 2 Einträge

10 mg Ag/m3 (NIOSH, 2024)

10.0 [mg/m3], as Ag

Toxikologische Informationen

Health Effects · 1 Eintrag

Silver itself is not toxic to humans, but most silver salts are. In large doses, silver and compounds containing it can be absorbed into the circulatory system and become deposited in various body tissues, leading to argyria, which results in a blue-grayish pigmentation of the skin, eyes, and mucous membranes. Argyria is rare, and although, so far as known, this condition does not otherwise harm a person's health, it is disfiguring and usually permanent. Mild forms of argyria are sometimes mistaken for cyanosis. (L809)

Exposure RoutesOral (L808) ; inhalation (L808) ; dermal (L808)
Toxicity Summary · 1 Eintrag

Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disrupting selenium-catalyzed sulfhydryl oxidation-reduction reactions and intracellular ion concentrations, respectively. Silver nanoparticles are believed to disrupt the mitochondrial respiratory chain, causing oxidative stress, reduced ATP synthesis, and DNA damage. (L808, A243, A244, A245, A246)

Signs and Symptoms · 1 Eintrag

Exposure to high levels of silver for a long period of time may result in a condition called arygria, a blue-gray discoloration of the skin and other body tissues. Argyria is a permanent effect but does not appear to be harmful to health. Exposure to high levels of silver in the air has resulted in breathing problems, lung and throat irritation, and stomach pains. Skin contact with silver can cause mild allergic reactions such as rash, swelling, and inflammation in some people. (L808)

Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).

Sicherheitsdaten

F
8
wgk
3
tsca
TSCA listed
ridadr
1759
hs_code
28432900
RTECS-Nr.
AJ4100000
risk_code
36/37/38-50
hazard_code
Xi,N
safety_code
26-36-37/39-61
hazard_class
9
Speicherklasse
11 - Combustible Solids
Hazard Classifications
Aquatic Acute 1Eye Irrit. 2Skin Irrit. 2STOT SE 3

VerwendenIn the health field, silver acetate-containing products have been used in gum, spray, and lozenges to deter smokers from smoking. The silver in these products, when mixed with smoke, creates an unpleasant metallic taste in the smoker's mouth, thus deterring them from smoking. Lozenges containing 2.5 mg of silver acetate showed "modest efficacy" on 500 adult smokers tested over a three-month period. However, over a period of 12 months, prevention failed. In 1974, silver acetate was first introduced in Europe as an over-thecounter smoking-deterrent lozenge (Repaton) and then three years later as a chewing gum (Tabmint).

Vor- und nachgelagerte Produkte

Nachgelagerte Produkte

Benzenemethanol, ar-methyl-, acetateLithiumacetat2-Propanone, 1-(acetyloxy)-3-bromo-Pentan-1,5-diyldiacetat1-Methyloctylacetat2-(3-(methoxycarbonyl)phenyl)acetic acidPropyltriacetoxysilan5-Brom-1H-indol-3-yl-acetatButan-2,3-diyldiacetat3-Acetoxyindol