6-Nitro-o-toluidin

2-Methyl-6-nitroaniline

HCID 11298CAS 570-24-1

Grundinformationen

Standard-SMILES
Cc1cccc([N+](=O)[O-])c1N
InChIKey
FCMRHMPITHLLLA-UHFFFAOYSA-N
Summenformel
C7H8N2O2
Durchschnittliche Molmasse
152,15 g/mol
Monoisotopische Masse
152,0585775

Überblick

2-methyl-6-nitroaniline appears as orange-yellow prisms or brown granular powder. (NTP, 1992)

Namen und Bezeichner

Bevorzugter Name
2-Methyl-6-nitroaniline
IUPAC
2-methyl-6-nitroaniline
Lokaler Name
6-Nitro-o-toluidin
Englischer Name
2-Methyl-6-nitroaniline
Summenformel
C7H8N2O2
Molmasse
152.15

Namen und Synonyme

2-METHYL-6-NITROANILINE570-24-12-Amino-3-nitrotoluene6-Nitro-o-toluidineBenzenamine, 2-methyl-6-nitro-6-Methyl-2-nitroaniline1-Amino-2-methyl-6-nitrobenzene3-Nitro-2-aminotolueneo-Toluidine, 6-nitro-2-nitro-6-methylanilineNSC 286OUP165YKBC
Weitere Namen anzeigen
2-Amino-3-nitro touleneNSC 52218-6-nitroaniL6-Nitro-o-tolLABOTEST-BB LTBB0006216-Nitro-2-Methylaniline
EINECS 209-329-62-Methyl-6-nitro-benzenamineIMEXINE FPNSC-286NSC-522182-amino-3-methylnitrobenzeneDTXSID7025631FCMRHMPITHLLLA-UHFFFAOYSA-

Datenbank-Bezeichner

CAS
570-24-1、60999-18-0
PubChem CID
11298
DTXSID
DTXSID7025631
UNII
OUP165YKBC
EC Number
209-329-6
Nikkaji
J28.416E

Eigenschaften

Berechnete Struktureigenschaften

XLogP
2
Polarare Oberfläche (TPSA)
71,8 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
0
Schwere Atome
11

Experimentelle und physikochemische Eigenschaften

Chemical ClassesNitrogen Compounds -> Nitroanilines
CosmeticsHair dyeing
SpringerMaterials PropertiesSurface tension
Density1.19 at 212 °F (NTP, 1992) - Denser than water; will sink
Solubilityless than 1 mg/mL at 73 °F (NTP, 1992)
Melting Point199 to 205 °F (NTP, 1992)

Physikochemische Eigenschaften

Schmelzpunkt
93 · 93-96 °C (lit.)
Siedepunkt
124 °C · 124 °C / 1mmHg
Dichte
1.19 g/cm3 · 1.19 g/cm3
Brechungsindex
1.6276 · 1.6276 (estimate)
Flammpunkt
110 °C · 110 °C
storage temp.
Keep in dark place,Inert atmosphere,Room temperature

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

P260, P261, P262, P264, P270, P271, P273, P280, P301+P316, P302+P352, P304+P340, P316, P319, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H311: Toxic in contact with skin [Danger Acute toxicity, dermal]

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: Benzenamine, 2-methyl-6-nitro-

Status: No longer Valid Update: 25-04-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/24595

6-Nitro-o-toluidine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Benzenamine, 2-methyl-6-nitro-: Human health tier II assessment
DOT LabelPoison
Fire HazardsFlash point data for this compound are not available, but it is probably combustible. (NTP, 1992)
Health HazardsExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:
Hazards Summary · 1 Eintrag

A mild skin and eye irritant in rabbits at 3% concentration in 1,2-propanediol; No evidence of skin sensitization in guinea pigs; Hepatotoxicity observed in 28-day oral studies of rats; No evidence of embryotoxicity or teratogenicity in rats; [EC: SCCNFP] May cause irritation; May induce methemoglobinemia; Toxic by ingestion, inhalation, and skin absorption; Targets the blood; [Sigma-Aldrich MSDS] See 2-Nitroaniline.

Sicherheit und Schutzausrüstung

Fire FightingFires involving this material can be controlled using a carbon dioxide, dry chemical or Halon extinguisher. (NTP, 1992)
First Aid · 1 Eintrag

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 Eintrag

SMALL SPILLS AND LEAKAGE: If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:
Personal Protective Equipment (PPE) · 1 Eintrag

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Toxikologische Informationen

Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Sicherheitsdaten

F
10
wgk
3
ridadr
UN 2660 6.1/PG 3
hs_code
29214300
risk_code
23/24/25-33-51/53
hazard_code
T,N,Xi

Chemie und Industrie

Verwendung und Herstellung

Uses · 2 Einträge

Used in semi-permanent hair dyes; [EC: SCCNFP]

Dressing Hair [Category: Other]

Use ClassificationCosmetics -> Hair dyeing

Anbieter50 Anbieter

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上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

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