Grundinformationen
- Standard-SMILES
[Pd].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1- InChIKey
NFHFRUOZVGFOOS-UHFFFAOYSA-N- Summenformel
- C72H60P4Pd
- Durchschnittliche Molmasse
- 1.155,6 g/mol
Überblick
Tetrakis(triphenylphosphine)palladium(0) is a coordination complex of palladium. It is widely used as a catalyst for coupling reactions. Palladium is a chemical element with the chemical symbol Pd and an atomic number of 46. It is found as a free metal alloyed with gold and other platinum group metals and in the rare minerals cooperite and polarite. (L794, L806)
Namen und Bezeichner
- Bevorzugter Name
- Tetrakis(triphenylphosphine)palladium
- IUPAC
- palladium;tetrakis(triphenylphosphane)
Namen und Synonyme
Tetrakis(triphenylphosphine)palladiumPD(PPH3)4Tetra(triphenylphosphine)palladiumPalladium, tetrakis(triphenylphosphine)-, (T-4)-EINECS 238-086-9N9O1RWZ93JDTXSID9065732palladiumtetrakis(triphenylphosphine)RefChem:897289DTXCID7034628Palladium, tetrakis(triphenylphosphine), (T4)238-086-9
Weitere Namen anzeigen
14221-01-3Tetrakis(triphenylphosphine)palladium(0)Tetrakis(triphenylphosphine) palladium(0)MFCD00010012palladium;triphenylphosphanePalladium-tetrakis(triphenylphosphine)Palladium (0) tetrakis(triphenylphosphine)tetrakis(triphenylphosphane) palladium
Datenbank-Bezeichner
- CAS
14221-01-3- PubChem CID
- 11979704
- DTXSID
DTXSID9065732- EC Number
- 238-086-9
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 0 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 0
- Frei drehbare Bindungen
- 12
- Schwere Atome
- 77
- Formalladung
- 0
- Komplexität
- 202
Experimentelle und physikochemische Eigenschaften
Chemical ClassesMetals -> Organic Compounds, Metal Salts
Physical DescriptionCrystals; [Sigma-Aldrich MSDS]
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 0.5% (1 of 193) of reports.
Warning
H302 (83.9%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P321, P330, P333+P317, P362+P364, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 193 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: Palladium, tetrakis(triphenylphosphine)-, (T-4)-
Status: Cease Manufacture Update: 18-11-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/19027
Palladium, tetrakis(triphenylphosphine)-, (T-4)-: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Palladium, tetrakis(triphenylphosphine)-, (T-4)-: Environment tier I assessment
Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS] See Palladium. See Triphenylphosphine.
Hazard Classes and CategoriesAcute Tox. 4 (83.9%)
Toxikologische Informationen
Health EffectsContact with palladium may cause palladium sensitivity and allergy. Animal studies have shown that palladium may damage the liver and kidney. (L798)
Toxicity Summary
Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, and interact with functional groups of macromolecules, such as proteins or DNA. Palladium complexes binding to DNA and RNA leads to strand breakage. Palladium ions are able to inhibit most major cellular functions, including DNA and RNA synthesis. Palladium compounds have been shown to bind to and inhibit various enzymes, including creatine kinase and prolyl hydroxylase. (L798)
Signs and SymptomsSkin contact with palladium may cause contact dermatitis, erythema, and oedema. (L798)
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).
Chemie und Industrie
Pharmakologische Informationen
Metabolism/Metabolites
Palladium may be absorbed through oral, dermal, and inhalation exposure. Once in the body it distributes to the kidney, liver, spleen, lymph nodes, adrenal gland, lung and bone. Palladium's ability to form complexes allows it the bind to amino acids, proteins, DNA, and other macromolecules. Palladium and its metabolites are excreted in the urine and faeces. (A21)
Verwendung und Herstellung
UsesTetrakis(triphenylphosphine)palladium(0) is widely used as a catalyst for coupling reactions. (L806)
General Manufacturing InformationPalladium, tetrakis(triphenylphosphine)-, (T-4)-: ACTIVE
Zugehörige Reaktionen
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