Ethylglykolat
Ethyl Glycolate
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Grundinformationen
- CAS
623-50-7- Standard-SMILES
CCOC(=O)CO- InChIKey
ZANNOFHADGWOLI-UHFFFAOYSA-N- Summenformel
- C4H8O3
- Durchschnittliche Molmasse
- 104,1 g/mol
- Monoisotopische Masse
- 104,04734411
Überblick
Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Ethyl Glycolate...
Namen und Bezeichner
- Bevorzugter Name
- Ethyl Glycolate
- IUPAC
- ethyl 2-hydroxyacetate
- Lokaler Name
- Ethylglykolat
- Englischer Name
- Ethyl glycolate
- Summenformel
- C4H8O3
- Molmasse
- 104.1
Namen und Synonyme
Ethyl glycolate623-50-7Ethyl hydroxyacetateHydroxyacetic acid ethyl esterGLYCOLIC ACID, ETHYL ESTEREthyl glycollateNSC 8835Acetic acid, 2-hydroxy-, ethyl esterC306E91WFKAI3-03541NSC-8835EINECS 210-798-4
Weitere Namen anzeigen
HOCH2COOC2H5EthylGlycolate>Ethyl glycolate,95%Ethyl glycolate 98%Ethyl glycolate ,98%ETHYL2-HYDROXYACETATE
BRN 17437664-03-00-00580 (Beilstein Handbook Reference)RefChem:596202Acetic acid, hydroxy, ethyl esterAcetic acid, 2hydroxy, ethyl esterethyl 2-hydroxyacetateAcetic acid, hydroxy-, ethyl esterMFCD00021970
Datenbank-Bezeichner
- CAS
623-50-7- PubChem CID
- 12184
- DTXSID
DTXSID5060772- UNII
- C306E91WFK
- EC Number
- 210-798-4
- Nikkaji
- J53.999F
Eigenschaften
Berechnete StruktureigenschaftenWird ergänzt
- XLogP
- -0,2
- Polarare Oberfläche (TPSA)
- 46,5 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 3
- Schwere Atome
- 7
- Formalladung
- 0
- Komplexität
- 60
Experimentelle und physikochemische Eigenschaften
Chemical ClassesOther Classes -> Esters, Other
CosmeticsCosmetic ingredients (Ethyl Glycolate) -> CIR (Cosmetic Ingredient Review)
SpringerMaterials PropertiesSchoenflies notation
Physical DescriptionClear colorless liquid; [Acros Organics MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 300 °C · >300 °C
- Siedepunkt
- 158 · 158-159 °C (lit.)
- Dichte
- 1.1 g/mL · 1.1 g/mL at 25 °C (lit.)
- Brechungsindex
- 20 · n20/D 1.419(lit.)
- Flammpunkt
- 143 °F · 143 °F
- storage temp.
- Sealed in dry,Room Temperature
- Löslichkeit
- Chloroform, Methanol (Slightly)
- pka
- 13.14 · 13.14±0.10(Predicted)
- Aggregatzustand
- Liquid
- Farbe
- Colorless
- Geruch (Odor)
- Peculiar ethereal, weedy-winey odour, often classified as "Spearmint-like".
- Wasserlöslichkeit
- 50 C · It is very soluble in water, alcohols, acetone, acetates, slightly soluble in ethyl ether, sparingly soluble in hydrocarbon solvents, polymerization occurs above 50 C.
- InChI
- 1S/C4H8O3/c1-2-7-4(6)3-5/h5H,2-3H2,1H3
- InChIKey
- ZANNOFHADGWOLI-UHFFFAOYSA-N
- SMILES
- CCOC(=O)CO
- CAS Datenbank
- 623 · 623-50-7(CAS DataBase Reference)
- NIST chemische Informationen
- Acetic acid, hydroxy-, ethyl ester(623-50-7)
- EPA chemische Informationen
- Acetic acid, hydroxy-, ethyl ester (623-50-7)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 45 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazards SummaryA mild eye irritant in guinea pigs; Causes general anesthesia, muscle weakness, and cyanosis in intraperitoneal lethal-dose studies of rats (LDLo = 1,500 mg/kg); [RTECS] An irritant; [Acros Organics MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Toxikologische Informationen
Adverse EffectsNeurotoxin - Acute solvent syndrome
Toxicity Summary
Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Ethyl Glycolate...
Safe for use in cosmetics, with qualifications
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- 1993
- hs_code
- 29181990
- RTECS-Nr.
- MC5410000
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36/37/39-37/39
- hazard_class
- 3.2
- packing_group
- III
- Speicherklasse
- 10 - Combustible liquids
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
Chemie und Industrie
Verwendung und Herstellung
UsesCIR ingredient: Ethyl Glycolate
General Manufacturing InformationAcetic acid, 2-hydroxy-, ethyl ester: ACTIVE
Anwendungen
VerwendenEthyl glycolate, is an important building block for the preparation of agrochemicals and medicinal compounds. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dye stuff. It is also used in synthetic chemistry, discovery process and R&D. It also can be used as solvents.
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