Ethylthioglykolat
Ethyl Thioglycolate
Grundinformationen
- CAS
623-51-8- Standard-SMILES
CCOC(=O)CS- InChIKey
PVBRSNZAOAJRKO-UHFFFAOYSA-N- Summenformel
- C4H8O2S
- Durchschnittliche Molmasse
- 120,17 g/mol
- Monoisotopische Masse
- 120,02450067
Überblick
Based on the available data, the CIR Expert Panel concluded that ... Ethyl Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure.
Namen und Bezeichner
- Bevorzugter Name
- Ethyl Thioglycolate
- IUPAC
- ethyl 2-sulfanylacetate
- Lokaler Name
- Ethylthioglykolat
- Englischer Name
- Ethyl Thioglycolate
- Summenformel
- C4H8O2S
- Molmasse
- 120.17
Namen und Synonyme
Ethyl thioglycolate623-51-8Ethyl 2-mercaptoacetateEthyl mercaptoacetateUSAF EK-2070Thioglykolsaeure-aethylesterEthyl .alpha.-mercaptoacetateAcetic acid, 2-mercapto-, ethyl ester2-mercaptoacetic acid ethyl esterNSC 8834UNII-Z5SD8DD6CPZ5SD8DD6CP
Weitere Namen anzeigen
THIOGLYCOLIC ACID ETHYL ESTERusafek-2070EthylthioglykolatEthyl thioglycolatEthylsulfanylacetatThioglycolate ethyl
EINECS 210-800-3Thioglykolsaeure-aethylester [German]BRN 0605581ETHOXYCARBONYLMETHANETHIOLAI3-23030NSC-8834Ethyl alpha-mercaptoacetate4-03-00-00616 (Beilstein Handbook Reference)
Datenbank-Bezeichner
- CAS
623-51-8- PubChem CID
- 12185
- DTXSID
DTXSID8049337
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 0,8
- Polarare Oberfläche (TPSA)
- 27,3 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 3
- Schwere Atome
- 7
- Formalladung
- 0
- Komplexität
- 62,7
Experimentelle und physikochemische Eigenschaften
Chemical ClassesOther Classes -> Esters, Other
Cosmetics
Cosmetic ingredients (Ethyl Thioglycolate) -> CIR (Cosmetic Ingredient Review)
Depilatory; Hair waving or straightening; Reducing
SpringerMaterials PropertiesOptical coefficient
Physical DescriptionColorless liquid with a stench; [Alfa Aesar MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- -80 °C · -80 °C
- Siedepunkt
- 157 °C · 157 °C
- Dichte
- 1.1 · 1.10
- Brechungsindex
- 1.46 · 1.46
- Flammpunkt
- 48 °C · 48 °C
- storage temp.
- 2 · Keep in dark place,Inert atmosphere,2-8°C
- pka
- 1 · pK1:7.95(SH) (25°C)
- Aggregatzustand
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H226 (98.1%): Flammable liquid and vapor [Warning Flammable liquids]
P210, P233, P240, P241, P242, P243, P264, P264+P265, P270, P280, P301+P316, P302+P352, P303+P361+P353, P305+P351+P338, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 53 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
REACH registered substance: Ethyl mercaptoacetate (EC: 210-800-3)
Ethyl thioglycolate: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryA mild eye irritant; Toxic by ingestion; [Alfa Aesar MSDS] See Thioglycolic acid.
Hazard Classes and CategoriesFlam. Liq. 3 (98.1%)
Toxikologische Informationen
Toxicity Summary
Based on the available data, the CIR Expert Panel concluded that ... Ethyl Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure.
Safe for use in cosmetics, with qualifications
Sicherheitsdaten
Chemie und Industrie
Verwendung und Herstellung
UsesCIR ingredient: Ethyl Thioglycolate
Use ClassificationCosmetics -> Depilatory; Hair waving or straightening; Reducing
General Manufacturing InformationAcetic acid, 2-mercapto-, ethyl ester: ACTIVE
Anwendungen
VerwendenIt finds its application in the reaction of the dilithio-derivative with an aldehyde, followed by conversion to the episulfide by reaction with ethyl chloroformate, and desulfurization with triethyl phosphite, leads to the (E)-2-alkenoic acid with high stereoselectivity. It is used as depilatories, hair straightening agent, hair waving agent, and reducing agent in cosmetic industry.
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