Ethylthioglykolat

Ethyl Thioglycolate

HCID 12185CAS 623-51-8
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Grundinformationen

Standard-SMILES
CCOC(=O)CS
InChIKey
PVBRSNZAOAJRKO-UHFFFAOYSA-N
Summenformel
C4H8O2S
Durchschnittliche Molmasse
120,17 g/mol
Monoisotopische Masse
120,0245005

Überblick

Based on the available data, the CIR Expert Panel concluded that ... Ethyl Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure.

Namen und Bezeichner

Bevorzugter Name
Ethyl Thioglycolate
IUPAC
ethyl 2-sulfanylacetate
Lokaler Name
Ethylthioglykolat
Englischer Name
Ethyl Thioglycolate
Summenformel
C4H8O2S
Molmasse
120.17

Namen und Synonyme

Ethyl thioglycolate623-51-8Ethyl 2-mercaptoacetateEthyl mercaptoacetateUSAF EK-2070Thioglykolsaeure-aethylesterNSC 8834Ethyl .alpha.-mercaptoacetateAcetic acid, 2-mercapto-, ethyl ester2-mercaptoacetic acid ethyl esterUNII-Z5SD8DD6CPZ5SD8DD6CP
Weitere Namen anzeigen
THIOGLYCOLIC ACID ETHYL ESTERusafek-2070EthylthioglykolatEthyl thioglycolatEthylsulfanylacetatThioglycolate ethyl
EINECS 210-800-3Thioglykolsaeure-aethylester [German]BRN 0605581AI3-23030NSC-8834Ethyl alpha-mercaptoacetateETHOXYCARBONYLMETHANETHIOL4-03-00-00616 (Beilstein Handbook Reference)

Datenbank-Bezeichner

CAS
623-51-8
PubChem CID
12185
DTXSID
DTXSID8049337
ChEMBL
CHEMBL3181965
UNII
Z5SD8DD6CP
EC Number
210-800-3
Nikkaji
J49.275B

Eigenschaften

Berechnete Struktureigenschaften

XLogP
0,8
Polarare Oberfläche (TPSA)
27,3 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
3
Schwere Atome
7

Experimentelle und physikochemische Eigenschaften

Chemical ClassesOther Classes -> Esters, Other
Cosmetics · 2 Einträge

Cosmetic ingredients (Ethyl Thioglycolate) -> CIR (Cosmetic Ingredient Review)

Hair waving or straightening; Reducing; Depilatory

SpringerMaterials PropertiesOptical coefficient
Physical DescriptionColorless liquid with a stench; [Alfa Aesar MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
-80 °C · -80 °C
Siedepunkt
54 °C/12 · 54 °C/12 mmHg (lit.)
Dichte
1.096 g/mL · 1.096 g/mL at 25 °C (lit.)
Brechungsindex
20 · n20/D 1.457(lit.)
Flammpunkt
118 °F · 118 °F
storage temp.
2 · Keep in dark place,Inert atmosphere,2-8°C

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Danger

H226 (98.1%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P264, P264+P265, P270, P280, P301+P316, P302+P352, P303+P361+P353, P305+P351+P338, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 53 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Status: Active Update: 03-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/34481

Ethyl thioglycolate: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryA mild eye irritant; Toxic by ingestion; [Alfa Aesar MSDS] See Thioglycolic acid.
Hazard Classes and CategoriesFlam. Liq. 3 (98.1%)

Toxikologische Informationen

Toxicity Summary · 2 Einträge

Based on the available data, the CIR Expert Panel concluded that ... Ethyl Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure.

Safe for use in cosmetics, with qualifications

Sicherheitsdaten

wgk
3
tsca
TSCA listed
ridadr
UN 1992 3/PG 3
hs_code
29309090
RTECS-Nr.
AI6650000
risk_code
10-25-36/38

Chemie und Industrie

Verwendung und Herstellung

UsesCIR ingredient: Ethyl Thioglycolate
Use ClassificationCosmetics -> Hair waving or straightening; Reducing; Depilatory
General Manufacturing InformationAcetic acid, 2-mercapto-, ethyl ester: ACTIVE
Anwendungen · 1 Eintrag

VerwendenIt finds its application in the reaction of the dilithio-derivative with an aldehyde, followed by conversion to the episulfide by reaction with ethyl chloroformate, and desulfurization with triethyl phosphite, leads to the (E)-2-alkenoic acid with high stereoselectivity. It is used as depilatories, hair straightening agent, hair waving agent, and reducing agent in cosmetic industry.

Vor- und nachgelagerte Produkte

Vorgelagerte Rohstoffe

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

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