1,4-Dichlorbut-2-in

1,4-Dichloro-2-butyne

HCID 13182
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Grundinformationen

CAS
821-10-3
Standard-SMILES
ClCC#CCCl
InChIKey
RCHDLEVSZBOHOS-UHFFFAOYSA-N
Summenformel
C4H4Cl2
Durchschnittliche Molmasse
122,98 g/mol
Monoisotopische Masse
121,9690055

Namen und Bezeichner

Bevorzugter Name
1,4-Dichloro-2-butyne
IUPAC
1,4-dichlorobut-2-yne
Lokaler Name
1,4-Dichlorbut-2-in
Englischer Name
1,4-Dichloro-2-butyne
Summenformel
C4H4Cl2
Molmasse
122.98

Namen und Synonyme

1,4-DICHLORO-2-BUTYNE821-10-32-Butyne, 1,4-dichloro-EINECS 212-474-8NSC 30603BRN 0635740AI3-269304-01-00-00973 (Beilstein Handbook Reference)DTXSID00611651,4Dichlorobutyne1,4Dichlorobut2yne2Butyne, 1,4dichloro
Weitere Namen anzeigen
DK925DKSI002DKFELEX0248Dichlorobutyne1,4-Dichlorbut-2-in1,4-dichloro-2-butyn1,4-dichloro-1-butyne1,4-dichlorobut-1-yne
RefChem:73228DTXCID0048264RCHDLEVSZBOHOS-UHFFFAOYSA-N1,4-Dichlorobut-2-yne1,4-DichlorobutyneC4H4Cl2MFCD000009811,4-dichloro-but-2-yne

Datenbank-Bezeichner

CAS
821-10-3
PubChem CID
13182
DTXSID
DTXSID0061165
UNII
9QW8CV4W9J
EC Number
212-474-8
Nikkaji
J2.114H

Eigenschaften

Berechnete Struktureigenschaften

XLogP
2
Polarare Oberfläche (TPSA)
0 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
0
Frei drehbare Bindungen
0
Schwere Atome
6

Experimentelle und physikochemische Eigenschaften

Vapor Pressure1.86 [mmHg]
Physical DescriptionColorless or pale yellow liquid; [Alfa Aesar MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
162 · 162-165 °C
Siedepunkt
165 · 165-168 °C (lit.)
Dichte
1.258 g/mL · 1.258 g/mL at 25 °C (lit.)
Brechungsindex
20 · n20/D 1.505(lit.)
Flammpunkt
320 °F · 320 °F
storage temp.
Keep in dark place,Sealed in dry,Room Temperature

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H301 (11.1%): Toxic if swallowed [Danger Acute toxicity, oral]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (95.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information1,4-Dichloro-2-butyne: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryAn irritant; Causes lachrymation; [Alfa Aesar MSDS] See Dichloroacetylene.
Hazard Classes and Categories · 2 Einträge

Acute Tox. 3 (11.1%)；Skin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；STOT SE 3 (95.6%)

Acute toxicity (Oral) - Category 3

Toxikologische Informationen

Adverse EffectsLacrimator (Lachrymator) - A substance that irritates the eyes and induces the flow of tears.

Regulatorische Informationen

Regulatory Information1,4-Dichloro-2-butyne: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

F
8-10
wgk
3
tsca
TSCA listed
ridadr
UN 2810
hs_code
29032900
RTECS-Nr.
ER9600000

Chemie und Industrie

Verwendung und Herstellung

General Manufacturing Information2-Butyne, 1,4-dichloro-: ACTIVE

Anwendungen

Verwenden1,4-Dichloro-2-butyne used in the synthesis of 1,4-disubstituted 1,2,3-triazoles. Also, it is used in the approach of the 20S-camptothecin family of antitumor agents.

Darstellung · 1 Eintrag

synthetische1,4-Dichloro-2-butyne could be conveniently prepared by treating 1,4-butynediol with Thionyl Chloride. However, as a precautionary measure, the medium is diluted with CH2Cl2 and cooled to 30°C before adding thionyl chloride to avoid hazards associated with the exothermicity of the reaction.

Vor- und nachgelagerte Produkte

Anbieter100 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
上海策嵘生物科技有限公司[email protected]

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