(R)-1,2-Epoxypropane (HCID 146261)

Überblick

(R)-1,2-epoxypropane is a 1,2-epoxypropane. It is an enantiomer of a (S)-1,2-epoxypropane.

Namen und Bezeichner

Bevorzugter Name: (R)-1,2-Epoxypropane
IUPAC: (2R)-2-methyloxirane
Englischer Name: (R)-(+)-Propylene oxide
Summenformel: C3H6O
Molmasse: 58.08

Namen und Synonyme

(2R)-2-methyloxirane(R)-1,2-Epoxypropane(+)-Propylene oxideOxirane, methyl-, (2R)-Oxirane, methyl-, (R)-Propylene oxide, (R)-(+)-CHEBI:28985EC 604-958-6DTXSID201320388(R)-(+)-1,2-Propylene oxideRefChem:407088DTXCID801749805

Weitere Namen anzeigen

(R)-2-Methyloxirane(R)-(+)-PropyLR(+)-METHYLOXIRANE(r)-(+)-propyleneoxidChiral Propylene Oxide

Oxirane, methyl-, (R)-(9CI)604-958-6(R)-(+)-propylene oxide15448-47-2(R)-Propylene oxide(R)-Methyloxirane(R)-Epoxypropane(+)-Methyloxirane

Datenbank-Bezeichner

CAS: 15448-47-2
PubChem CID: 146261
DTXSID: DTXSID201320388
ChEMBL: CHEMBL1901974
ChEBI: CHEBI:28985
EC Number: 604-958-6
Nikkaji: J471.948D

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 0
Polarare Oberfläche (TPSA): 12,5 Å²
H-Brücken-Donoren: 0
H-Brücken-Akzeptoren: 1
Frei drehbare Bindungen: 0
Schwere Atome: 4
Formalladung: 0
Komplexität: 26,5

Experimentelle und physikochemische Eigenschaften

DrugsPharmaceuticals -> Listed in ZINC15

Physikochemische Eigenschaften

Schmelzpunkt: -111.91 °C · -111.91°C (estimate)
Siedepunkt: 33 · 33-34 °C(lit.)
Dichte: 0.829 g/mL · 0.829 g/mL at 20 °C(lit.)
Dampfdruck: 588 hPa · 588 hPa (20 °C)
Brechungsindex: 20 · n20/D 1.366(lit.)
Flammpunkt: -31 °F · -31 °F
storage temp.: 20 °C · Store at <= 20°C.
Löslichkeit: 405 g/l · 405g/l
Aggregatzustand: clear liquid
Farbe: Colorless to Almost colorless
Explosionsgrenze: 1.9 · 1.9-37%(V)
Wasserlöslichkeit: Miscible with water and many organic solvents.
Merck: 14 · 14,7856
BRN: 79764 · 79764
InChI: 1S/C3H6O/c1-3-2-4-3/h3H,2H2,1H3/t3-/m1/s1
InChIKey: GOOHAUXETOMSMM-GSVOUGTGSA-N
SMILES: C[C@@H]1CO1
LogP: 0.03 · 0.03-0.085
CAS Datenbank: 15448 · 15448-47-2(CAS DataBase Reference)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H224 (100%): Extremely flammable liquid and vapor [Danger Flammable liquids]

P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: Oxirane, methyl-, (R)-

Status: Active Update: 28-02-2011 https://echa.europa.eu/registration-dossier/-/registered-dossier/6315

(R)-(+)-1,2-Propylene oxide: HSNO Approval: HSR004105 Approved with controls

Other Safety InformationIMAP assessments - Methyloxirane (R-, S- and (R,S)-): Human health tier II assessment

Hazard Classes and Categories · 2 Einträge

Flam. Liq. 1 (100%)

Acute toxicity - category 4

Sicherheitsdaten

wgk: 3
ridadr: UN 1280 3/PG 1
hs_code: 2910 20 00
RTECS-Nr.: UJ2650000
risk_code: 12-25-2017/12/25
Toxizität: LD50 orally in Rabbit: 380 mg/kg LD50 dermal Rabbit 1243 mg/kg
hazard_code: F+,T
safety_code: 45
hazard_class: 3
packing_group: I
Speicherklasse: 3 - Flammable liquids
Hazard Classifications: Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 4 OralCarc. 1BEye Irrit. 2Flam. Liq. 1Muta. 1BSkin Irrit. 2STOT SE 3
Selbstentzündungstemperatur: 430 °C DIN 51794

Chemie und Industrie

Anwendungen · 1 Eintrag

Verwenden(R)-(+)-Propylene oxide is widely utilized in the manufacture of polyether polyols and propylene glycol, which is used to make the polyurethane plastics. It finds application as a fumigant for the sterilization of packaged foods and plastic medical instruments. Combine with ethanol, it used to make biological samples for electron microscopy. It also used in model aircraft and surface vehicles as a glow fuel.