2-(2H-Benzotriazol-2-yl)-p-kresol

Drometrizole

HCID 17113CAS 2440-22-4

Grundinformationen

Standard-SMILES
Cc1ccc(O)c(-n2nc3ccccc3n2)c1
InChIKey
MCPKSFINULVDNX-UHFFFAOYSA-N
Summenformel
C13H11N3O
Durchschnittliche Molmasse
225,25 g/mol
Monoisotopische Masse
225,09021198

Namen und Bezeichner

Bevorzugter Name
Drometrizole
IUPAC
2-(benzotriazol-2-yl)-4-methylphenol
Lokaler Name
2-(2H-Benzotriazol-2-yl)-p-kresol
Englischer Name
Drometrizole
Summenformel
C13H11N3O
Molmasse
225.25

Namen und Synonyme

Drometrizole2440-22-42-(2-HYDROXY-5-METHYLPHENYL)BENZOTRIAZOLE2-(2H-Benzotriazol-2-yl)-4-methylphenolDrometrizol2-(2'-Hydroxy-5'-methylphenyl)benzotriazoleDrometrizolumPhenol, 2-(2H-benzotriazol-2-yl)-4-methyl-DTXSID10274795X93W9OFZLNSC-91885DTXCID207479
Weitere Namen anzeigen
UV-PUV-712-(2H-1,2,3-Benzotriazol-2-yl)-4-methylphenolBenazol IIRIASORB UV-P
219-470-5RefChem:590441607-063-9Benazol P2-(2H-Benzotriazol-2-yl)-p-cresolTinuvin P2-(2H-benzo[d][1,2,3]triazol-2-yl)-4-methylphenol2-(2-Benzotriazolyl)-p-cresol

Datenbank-Bezeichner

CAS
2440-22-4
PubChem CID
17113
DTXSID
DTXSID1027479
ChEMBL
CHEMBL1564747
ChEBI
CHEBI:134926
UNII
5X93W9OFZL
EC Number
219-470-5、607-063-9
Nikkaji
J7.899I

Eigenschaften

Berechnete Struktureigenschaften

XLogP
4,3
Polarare Oberfläche (TPSA)
50,9 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
1
Schwere Atome
17

Experimentelle und physikochemische Eigenschaften

Physical DescriptionDry Powder; Other Solid; Large Crystals
Collision Cross Section155.4 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID1027479]

Physikochemische Eigenschaften

Schmelzpunkt
125.5 · 125.5-129.5 °C(lit.)
Siedepunkt
10 · bp10 225°
Dichte
1.38 · 1.38
Dampfdruck
0 Pa · 0Pa at 20℃
Brechungsindex
1.56 · 1.5600 (estimate)
Flammpunkt
54 °C · 54°C

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 0.8% (7 of 885) of reports.

Warning

H317 (97.1%): May cause an allergic skin reaction [Warning Sensitization, Skin];H410 (47%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard];H413 (46%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]

P261, P272, P273, P280, P302+P352, P321, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 885 reports by companies from 19 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 7 of 885 reports by companies.;There are 18 notifications provided by 878 of 885 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-

Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 31-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/13300

Drometrizole: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Phenolic benzotriazoles: Environment tier II assessment
Hazard Classes and Categories · 2 Einträge

Skin Sens. 1 (97.1%);Aquatic Chronic 1 (47%);Aquatic Chronic 4 (46%)

Skin sensitization - Category 1B;Specific target organ toxicity - Single exposure - Category 1 (respiratory organs);Specific target organ toxicity - Repeated exposure - Category 2 (kidney);Hazardous to the aquatic environment (Long-term) - Category 1

Toxikologische Informationen

Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

Regulatorische Informationen

Regulatory Information · 4 Einträge

Chemical: Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-

Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 31-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/13300

Drometrizole: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

wgk
1
tsca
TSCA listed
hs_code
29339900
RTECS-Nr.
GO6860000
risk_code
36/37/38-53-43
Toxizität
LD50 oral in mouse: 6500mg/kg

Chemie und Industrie

Verwendung und Herstellung

Uses · 2 Einträge

CIR ingredient: Drometrizole

Plastics -> Typical concentration range in plastic materials -> 0.0015 - 0.5%

U.S. Production2023: 100,000 - <250,000 lb;2022: 700,000 - <850,000 lb;2021: 700,000 - <850,000 lb;2020: 550,000 - <700,000 lb
Consumer UsesOther;UV stabilizer;Antioxidant
Industry UsesUV stabilizer;Antioxidant
Household ProductsInformation on 1 consumer products that contain Drometrizole in the following categories is provided:;• Home Maintenance
Use Classification · 5 Einträge

Fragrance Ingredients

Plastics -> Light stabilisers

Plastics -> Other functions -> Other stabiliser

Cosmetics -> Uv absorber

Plastics -> Polymer Type -> Polyolefin-I; Polyolefin-II; PVC (soft); ABS; PVC (rigid); PMMA; (E)PS

Anwendungen

VerwendenDrometrizole is an intermediate reactant in the synthesis of UV light absorbers for polyester fibers.

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海创欣化学有限公司021-54253545

Ergänzende Hinweise

DefinitionDrometrizole is a member of triazoles.

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52

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