Grundinformationen
- Standard-SMILES
CCNCC.O=S(=O)(O)c1cc(O)ccc1O- InChIKey
HBGOLJKPSFNJSD-UHFFFAOYSA-N- Summenformel
- C10H17NO5S
- Durchschnittliche Molmasse
- 263,31 g/mol
- Monoisotopische Masse
- 263,08274382
Namen und Bezeichner
- Bevorzugter Name
- Etamsylate
- IUPAC
- 2,5-dihydroxybenzenesulfonic acid;N-ethylethanamine
- Lokaler Name
- Etamsylat
- Englischer Name
- Etamsylate
- Summenformel
- C10H17NO5S
- Molmasse
- 263.31
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
2624-44-4- PubChem CID
- 17506
- DTXSID
DTXSID4045559- ChEMBL
CHEMBL1514715- ChEBI
CHEBI:31563- UNII
- 24YL531VOH
- EC Number
- 220-090-7
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 115 Ų
- H-Brücken-Donoren
- 4
- H-Brücken-Akzeptoren
- 6
- Frei drehbare Bindungen
- 3
- Schwere Atome
- 17
- Formalladung
- 0
- Komplexität
- 252
Physikochemische Eigenschaften
- Schmelzpunkt
- 125 ° · 125°
- Dichte
- 1.3441 · 1.3441 (rough estimate)
- Brechungsindex
- 1.506 · 1.5060 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Löslichkeit
- Very soluble in water, freely soluble in methanol, soluble in anhydrous ethanol, practically insoluble in methylene chloride.
- Aggregatzustand
- Solid
- Farbe
- White to Pale Red
- Merck
- 14 · 14,3722
- Stabilität
- Hygroscopic
- InChI
- InChI=1S/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3
- InChIKey
- HBGOLJKPSFNJSD-UHFFFAOYSA-N
- SMILES
- C1(S(=O)(=O)O)=CC(=CC=C1O)O.N(CC)CC
- CAS Datenbank
- 2624 · 2624-44-4(CAS DataBase Reference)
- EPA chemische Informationen
- Ethamsylate (2624-44-4)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 12.2% (5 of 41) of reports.
Warning
H319 (85.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)
Aggregated GHS information provided per 41 reports by companies from 3 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 5 of 41 reports by companies.;There are 2 notifications provided by 36 of 41 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Gefahrenhinweise
Regulatorische Informationen
Sicherheitsdaten
- wgk
- WGK 3
- tsca
- TSCA listed
- hs_code
- 2921.19.6190
- RTECS-Nr.
- DB6145000
- Toxizität
- LD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve)
- hazard_class
- IRRITANT
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Pharmakologische Informationen
ATC Code
B02BX01
B - Blood and blood forming organs;B02 - Antihemorrhagics;B02B - Vitamin k and other hemostatics;B02BX - Other systemic hemostatics;B02BX01 - Etamsylate
QB - Blood and blood forming organs;QB02 - Antihemorrhagics;QB02B - Vitamin k and other hemostatics;QB02BX - Other systemic hemostatics;QB02BX01 - Etamsylate
MeSH Pharmacological Classification
Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.
Verwendung und Herstellung
Anwendungen
VerwendenHemostatic;prostaglandin synthesis inhibitor
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