Chloride → 2,5-Dihydroxybenzenesulfonic Acid

HRID 1764363

Reaktionsgleichung

Reaktionsgleichung von HRID 1764363
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[S:9]([OH:12])(=[O:11])=[O:10].C(NCC)C.[Cl-].ClC1C=CC(OC(C)(C)C(O)=O)=CC=1>N1C=CC=CC=1>[OH:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[S:9]([OH:12])(=[O:10])=[O:11]

Komponenten

5

Edukt 3

HCID 312ChlorideHCID 2797Clofibric AcidHCID 17506Etamsylate

Produkt 1

HCID 175072,5-Dihydroxybenzenesulfonic Acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

To a solution of 263 g of diethylamine 2,5-dihydroxy benzene sulfonate in 500 ml of pyridine, 470 g of the chloride of p-chloro phenoxy isobutyric acid are added with stirring. The reaction is exothermic, but it is effected without refrigeration, letting it cool to ambiant temperature. A coloured precipitate forms, which is filtered and washed with water, and then copiously with ethanol. Thus 601 g of the pyridine salt of the di-O-(p-chloro phenoxy isobutyrate) of 2,5-dihydroxy benzene sulfonic acid are obtained in the form of a white crystalline powder having a melting point of 186°-188° C.

Aufarbeitung

  1. temperaturecool to ambiant temperature
  2. filtrationA coloured precipitate forms, which is filtered
  3. washwashed with water

Quellen und Nachweise

ORD-Eintrag
ord-f822306b9ec1432aa819205268cf2789
Quelldatensatz
uspto-grants-1978_09
Patentnummer
US04115648

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