Norleucin
Caprine
Grundinformationen
- CAS
327-57-1- Standard-SMILES
CCCC[C@H](N)C(=O)O- InChIKey
LRQKBLKVPFOOQJ-YFKPBYRVSA-N- Summenformel
- C6H13NO2
- Durchschnittliche Molmasse
- 131,17 g/mol
- Monoisotopische Masse
- 131,09462866
Überblick
L-norleucine is a non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally. It is a 2-aminohexanoic acid and a non-proteinogenic L-alpha-amino acid. It is a conjugate acid of a L-2-aminohexanoate. It is an enantiomer of a D-norleucine. It is a tautomer of a L-2-aminohexanoic acid zwitterion.
Namen und Bezeichner
- Bevorzugter Name
- Caprine
- IUPAC
- (2S)-2-aminohexanoic acid
- Lokaler Name
- Norleucin
- Englischer Name
- L-Norleucine
- Summenformel
- C6H13NO2
- Molmasse
- 131.17
Namen und Synonyme
L-Norleucine327-57-1NORLEUCINE(S)-2-Aminohexanoic acidCaprine(2S)-2-aminohexanoic acidGlycoleucineL-(+)-NorleucineL-2-Aminohexanoic acid2-Aminocaproic acidHexanoic acid, 2-amino-, (S)-L-Aminohexanoate
Weitere Namen anzeigen
NleH-NLE-OHG123Nle-OHL-Nle-OHH-L-NLE-OHH-AHX(2)-OH
alpha-Aminocaproic acidL-Aminohexanoic acid832C8OV84SNSC-10378CHEBI:18347DTXSID70883362Norleucine, LL-Isomer Norleucine
Datenbank-Bezeichner
- CAS
327-57-1、616-06-8- PubChem CID
- 21236
- DTXSID
DTXSID70883362- ChEMBL
CHEMBL292439- ChEBI
CHEBI:18347- UNII
- 832C8OV84S
- EC Number
- 206-321-4
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -1,5
- Polarare Oberfläche (TPSA)
- 63,3 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 9
- Formalladung
- 0
- Komplexität
- 93,1
Experimentelle und physikochemische Eigenschaften
LipidsFatty Acyls [FA] -> Fatty Acids and Conjugates [FA01] -> Amino fatty acids [FA0110]
LogP-1.53
Solubility12 mg/mL at 25 °C
Physical DescriptionSolid
Collision Cross Section
132 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
140.07 Ų [M-H]- [CCS Type: DT; Method: stepped-field]
129.02 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
136.4 Ų [M+H]+
Physikochemische Eigenschaften
- Schmelzpunkt
- 300 °C · >300 °C (lit.)
- Dichte
- 1.172 · 1.1720 (estimate)
- Brechungsindex
- 23 ° · 23 ° (C=5, 5mol/L HCl)
- Flammpunkt
- 275 °C · 275 °C
- storage temp.
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 7.1% (3 of 42) of reports.
Warning
H317 (90.5%): May cause an allergic skin reaction [Warning Sensitization, Skin]
P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 42 reports by companies from 3 notifications to the ECHA C&L Inventory.
Gefahrenhinweise
Regulatory Information
Chemical: L-Norleucine
L-Norleucine: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - L-Norleucine: Environment tier I assessment
Hazard Classes and CategoriesSkin Sens. 1 (90.5%)
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29224995
- RTECS-Nr.
- RC6308000
- risk_code
- 43
- hazard_code
- Xi
- safety_code
- 36/37-24/25-22
- Speicherklasse
- 11 - Combustible Solids
- Hazard Classifications
- Skin Sens. 1
Chemie und Industrie
Pharmakologische Informationen
Tissue LocationsPlatelet
Verwendung und Herstellung
General Manufacturing Information
L-Norleucine: ACTIVE
Norleucine: INACTIVE
Anwendungen
VerwendenAs a non-essential amino acid, L-Norleucine can be used as internal standard in amino acid analysis.
Vor- und nachgelagerte Produkte
Nachgelagerte Produkte
Ergänzende Hinweise
DefinitionChEBI: A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally.
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