Norleucin

Caprine

HCID 21236CAS 327-57-1
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Grundinformationen

Standard-SMILES
CCCC[C@H](N)C(=O)O
InChIKey
LRQKBLKVPFOOQJ-YFKPBYRVSA-N
Summenformel
C6H13NO2
Durchschnittliche Molmasse
131,17 g/mol
Monoisotopische Masse
131,09462866

Überblick

L-norleucine is a non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally. It is a 2-aminohexanoic acid and a non-proteinogenic L-alpha-amino acid. It is a conjugate acid of a L-2-aminohexanoate. It is an enantiomer of a D-norleucine. It is a tautomer of a L-2-aminohexanoic acid zwitterion.

Namen und Bezeichner

Bevorzugter Name
Caprine
IUPAC
(2S)-2-aminohexanoic acid
Lokaler Name
Norleucin
Englischer Name
L-Norleucine
Summenformel
C6H13NO2
Molmasse
131.17

Namen und Synonyme

L-Norleucine327-57-1NORLEUCINE(S)-2-Aminohexanoic acidCaprine(2S)-2-aminohexanoic acidGlycoleucineL-(+)-NorleucineL-2-Aminohexanoic acid2-Aminocaproic acidHexanoic acid, 2-amino-, (S)-L-Aminohexanoate
Weitere Namen anzeigen
NleH-NLE-OHG123Nle-OHL-Nle-OHH-L-NLE-OHH-AHX(2)-OH
alpha-Aminocaproic acidL-Aminohexanoic acid832C8OV84SNSC-10378CHEBI:18347DTXSID70883362Norleucine, LL-Isomer Norleucine

Datenbank-Bezeichner

CAS
327-57-1、616-06-8
PubChem CID
21236
DTXSID
DTXSID70883362
ChEMBL
CHEMBL292439
ChEBI
CHEBI:18347
UNII
832C8OV84S
EC Number
206-321-4
Nikkaji
J9.189H

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-1,5
Polarare Oberfläche (TPSA)
63,3 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
4
Schwere Atome
9

Experimentelle und physikochemische Eigenschaften

LipidsFatty Acyls [FA] -> Fatty Acids and Conjugates [FA01] -> Amino fatty acids [FA0110]
LogP-1.53
Solubility12 mg/mL at 25 °C
Physical DescriptionSolid
Collision Cross Section · 4 Einträge

132 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

142.63 Ų [M+H]+ [CCS Type: DT; Method: stepped-field]

129.02 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]

136.4 Ų [M+H]+

Physikochemische Eigenschaften

Schmelzpunkt
300 °C · >300 °C (lit.)
Dichte
1.172 · 1.1720 (estimate)
Brechungsindex
23 ° · 23 ° (C=5, 5mol/L HCl)
Flammpunkt
275 °C · 275 °C
storage temp.
Sealed in dry,Room Temperature
Löslichkeit
1.6 g/100 · 1.6 g/100 mL (23°C)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 7.1% (3 of 42) of reports.

Warning

H317 (90.5%): May cause an allergic skin reaction [Warning Sensitization, Skin]

P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 42 reports by companies from 3 notifications to the ECHA C&L Inventory.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Chemical: L-Norleucine

L-Norleucine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - L-Norleucine: Environment tier I assessment
Hazard Classes and CategoriesSkin Sens. 1 (90.5%)

Sicherheitsdaten

wgk
3
tsca
TSCA listed
hs_code
29224995
RTECS-Nr.
RC6308000
risk_code
43
hazard_code
Xi

Chemie und Industrie

Pharmakologische Informationen

Tissue LocationsPlatelet

Verwendung und Herstellung

General Manufacturing Information · 2 Einträge

L-Norleucine: ACTIVE

Norleucine: INACTIVE

Anwendungen

VerwendenAs a non-essential amino acid, L-Norleucine can be used as internal standard in amino acid analysis.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally.

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