Ganciclovir Sodium
Grundinformationen
- CAS
107910-75-8- Standard-SMILES
Nc1nc([O-])c2ncn(COC(CO)CO)c2n1.[Na+]- InChIKey
JJICLMJFIKGAAU-UHFFFAOYSA-M- Summenformel
- C9H12N5NaO4
- Durchschnittliche Molmasse
- 277,21 g/mol
- Monoisotopische Masse
- 277,07869816
Überblick
Ganciclovir Sodium can cause developmental toxicity and male reproductive toxicity according to state or federal government labeling requirements.
Namen und Bezeichner
- Bevorzugter Name
- Ganciclovir Sodium
- IUPAC
- sodium 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)purin-6-olate
- Englischer Name
- Ganciclovir sodium
- Summenformel
- C9H14N5NaO4
- Molmasse
- 279.23
Namen und Synonyme
GANCICLOVIR SODIUM107910-75-8Ganciclovir Sodium SaltCytovene IVCytovene-IVRS-21592 sodiumGanciclovir (as sodium)DTXSID20883175DHPG SodiumGCV Sodium02L083W2849-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine, monosodium salt
Weitere Namen anzeigen
Unii-02L083W284Rs 21592 sodiumSodium GanciclovirCytovene IV sodiumGancyclovir sodiumGanciclovir Impurity 7Ganciclovir sodium, >=98%Ganciclovir monosodium salt
denosineRefChem:56510DTXCID201022732BW-759BIOLF-6284245-13-6NatclovirGanciclovir (sodium)
Datenbank-Bezeichner
- CAS
107910-75-8、84245-13-6- PubChem CID
- 23700083
- DTXSID
DTXSID20883175- ChEMBL
CHEMBL1200850
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 142 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 8
- Frei drehbare Bindungen
- 5
- Schwere Atome
- 19
- Formalladung
- 0
- Komplexität
- 273
Experimentelle und physikochemische Eigenschaften
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Physikochemische Eigenschaften
- storage temp.
- 4 °C, · Store at 4°C, protect from light
- Löslichkeit
- 5 mg/mL · DMSO: 5 mg/mL (17.91 mM)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- Wasserlöslichkeit
- 50 mg/mL · Water: 50 mg/mL (179.06 mM)
- InChI
- InChI=1S/C9H13N5O4.Na.H/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16;;/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17);;
- InChIKey
- HKZYYRUGZQKKFS-UHFFFAOYSA-N
- SMILES
- C(N1C=NC2C(NC(N)=NC1=2)=O)OC(CO)CO.[NaH]
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H350 (100%): May cause cancer [Danger Carcinogenicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Gefahrenhinweise
Regulatory InformationHazard Traits - Developmental Toxicity; Reproductive Toxicity
Hazard Classes and CategoriesCarc. 1B (100%)
Toxikologische Informationen
Drug Induced Liver Injury
Drug Induced Liver Injury Rank (DILIrank 2.0)
Ganciclovir sodium
Ambiguous-DILI-concern
7
Adverse reactions
DOI:10.1016/j.drudis.2016.02.015
Sicherheitsdaten
- Alarmwort
- Warnung
- Gefahrenhinweise
- Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302
Chemie und Industrie
Pharmakologische Informationen
FDA Pharmacological Classification
GANCICLOVIR SODIUM
Nucleoside Analog Antiviral [EPC]; Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]; Nucleoside Analog [EXT]; DNA Polymerase Inhibitors [MoA]
MeSH Pharmacological Classification
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Anwendungen
VerwendenGanciclovir Sodium Salt is an inhibitor of the Herpesvirus family. It can be used in analytical study of establishment of a Raman database for non-invasive and rapid screening of liquid injectables.
Anbieter100 Anbieter
湖北威德利化学试剂有限公司186-02735115 18062128043 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
河南多贝化工有限公司0370-6999054 17550096163 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
湖北金梭生物科技有限公司00123456789 · [email protected]
Shanghai Yingrui Biopharma Co.,Ltd21-33585366 · [email protected]
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